Search Results for author: Adam Kapelner

Found 7 papers, 3 papers with code

Towards Outcome-Driven Patient Subgroups: A Machine Learning Analysis Across Six Depression Treatment Studies

no code implementations24 Mar 2023 David Benrimoh, Akiva Kleinerman, Toshi A. Furukawa, Charles F. Reynolds III, Eric Lenze, Jordan Karp, Benoit Mulsant, Caitrin Armstrong, Joseph Mehltretter, Robert Fratila, Kelly Perlman, Sonia Israel, Myriam Tanguay-Sela, Christina Popescu, Grace Golden, Sabrina Qassim, Alexandra Anacleto, Adam Kapelner, Ariel Rosenfeld, Gustavo Turecki

We analyzed data from six clinical trials of pharmacological treatment for depression (total n = 5438) using the Differential Prototypes Neural Network (DPNN), a neural network model that derives patient prototypes which can be used to derive treatment-relevant patient clusters while learning to generate probabilities for differential treatment response.

Better Experimental Design by Hybridizing Binary Matching with Imbalance Optimization

no code implementations6 Dec 2020 Abba M. Krieger, David Azriel, Adam Kapelner

This rate benefits from the greedy switching heuristic which is $O_p(n^{-3})$ and the rate of matching which is $O_p(n^{-1})$.

Methodology

Inference for the Effectiveness of Personalized Medicine with Software

1 code implementation30 Apr 2014 Adam Kapelner, Justin Bleich, Alina Levine, Zachary D. Cohen, Robert J. DeRubeis, Richard Berk

We demonstrate our method's promise on simulated data as well as on data from a randomized trial investigating two treatments for depression.

Methodology

Peeking Inside the Black Box: Visualizing Statistical Learning with Plots of Individual Conditional Expectation

6 code implementations25 Sep 2013 Alex Goldstein, Adam Kapelner, Justin Bleich, Emil Pitkin

This article presents Individual Conditional Expectation (ICE) plots, a tool for visualizing the model estimated by any supervised learning algorithm.

Applications

Prediction with Missing Data via Bayesian Additive Regression Trees

no code implementations3 Jun 2013 Adam Kapelner, Justin Bleich

We present a method for incorporating missing data in non-parametric statistical learning without the need for imputation.

Imputation regression

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