no code implementations • 4 Oct 2021 • Alex L. Payne-Dwyer, Aisha H. Syeda, Jack W. Shepherd, Lewis Frame, Mark. C. Leake
The RecA protein and RecBCD complex are key bacterial components for the maintenance and repair of DNA, RecBCD a helicase-nuclease that uses homologous recombination to resolve double-stranded DNA breaks and also facilitating decoration of single-stranded DNA with RecA to form RecA filaments, a vital step in the double-stranded break DNA repair pathway.
no code implementations • 22 Feb 2021 • Adam J. M Wollman, Aisha H. Syeda, Andrew Leech, Colin Guy, Peter McGlynn, Michelle Hawkins, Mark C. Leake
DNA replication in all organisms must overcome nucleoprotein blocks to complete genome duplication.