no code implementations • 23 Nov 2023 • Innokentiy Kastalskiy, Andrei Zinovyev, Evgeny Mirkes, Victor Kazantsev, Alexander N. Gorban
In the context of natural disasters, human responses inevitably intertwine with natural factors.
1 code implementation • 28 Aug 2022 • Evgeny M Mirkes, Jonathan Bac, Aziz Fouché, Sergey V. Stasenko, Andrei Zinovyev, Alexander N. Gorban
Domain adaptation is a popular paradigm in modern machine learning which aims at tackling the problem of divergence (or shift) between the labeled training and validation datasets (source domain) and a potentially large unlabeled dataset (target domain).
no code implementations • 10 Aug 2022 • Alexander Chervov, Andrei Zinovyev
One of the major difficulties for existing packages is distinguishing between two patterns of cell cycle transcriptomic dynamics: normal and characteristic for embryonic stem cells (ESC), with the latter one shared by many cancer cell lines.
no code implementations • 30 Mar 2022 • Qinghua Zhou, Alexander N. Gorban, Evgeny M. Mirkes, Jonathan Bac, Andrei Zinovyev, Ivan Y. Tyukin
Recent work by Mellor et al (2021) showed that there may exist correlations between the accuracies of trained networks and the values of some easily computable measures defined on randomly initialised networks which may enable to search tens of thousands of neural architectures without training.
1 code implementation • 6 Sep 2021 • Jonathan Bac, Evgeny M. Mirkes, Alexander N. Gorban, Ivan Tyukin, Andrei Zinovyev
Dealing with uncertainty in applications of machine learning to real-life data critically depends on the knowledge of intrinsic dimensionality (ID).
1 code implementation • 7 Jul 2020 • Sergey E. Golovenkin, Jonathan Bac, Alexander Chervov, Evgeny M. Mirkes, Yuliya V. Orlova, Emmanuel Barillot, Alexander N. Gorban, Andrei Zinovyev
Large observational clinical datasets become increasingly available for mining associations between various disease traits and administered therapy.
no code implementations • 31 Jan 2020 • Jonathan Bac, Andrei Zinovyev
In this paper, we introduce new local estimators of ID based on linear separability of multi-dimensional data point clouds, which is one of the manifestations of concentration of measure.
no code implementations • 10 Sep 2019 • Stéphanie Chevalier, Christine Froidevaux, Loïc Paulevé, Andrei Zinovyev
Boolean networks model finite discrete dynamical systems with complex behaviours.
1 code implementation • 18 Jan 2019 • Luca Albergante, Jonathan Bac, Andrei Zinovyev
Modern large-scale datasets are frequently said to be high-dimensional.
2 code implementations • 20 Apr 2018 • Luca Albergante, Evgeny M. Mirkes, Huidong Chen, Alexis Martin, Louis Faure, Emmanuel Barillot, Luca Pinello, Alexander N. Gorban, Andrei Zinovyev
Large datasets represented by multidimensional data point clouds often possess non-trivial distributions with branching trajectories and excluded regions, with the recent single-cell transcriptomic studies of developing embryo being notable examples.
2 code implementations • 11 Oct 2017 • Laurent Heirendt, Sylvain Arreckx, Thomas Pfau, Sebastián N. Mendoza, Anne Richelle, Almut Heinken, Hulda S. Haraldsdóttir, Jacek Wachowiak, Sarah M. Keating, Vanja Vlasov, Stefania Magnusdóttir, Chiam Yu Ng, German Preciat, Alise Žagare, Siu H. J. Chan, Maike K. Aurich, Catherine M. Clancy, Jennifer Modamio, John T. Sauls, Alberto Noronha, Aarash Bordbar, Benjamin Cousins, Diana C. El Assal, Luis V. Valcarcel, Iñigo Apaolaza, Susan Ghaderi, Masoud Ahookhosh, Marouen Ben Guebila, Andrejs Kostromins, Nicolas Sompairac, Hoai M. Le, Ding Ma, Yuekai Sun, Lin Wang, James T. Yurkovich, Miguel A. P. Oliveira, Phan T. Vuong, Lemmer P. El Assal, Inna Kuperstein, Andrei Zinovyev, H. Scott Hinton, William A. Bryant, Francisco J. Aragón Artacho, Francisco J. Planes, Egils Stalidzans, Alejandro Maass, Santosh Vempala, Michael Hucka, Michael A. Saunders, Costas D. Maranas, Nathan E. Lewis, Thomas Sauter, Bernhard Ø. Palsson, Ines Thiele, Ronan M. T. Fleming
This protocol can be adapted for the generation and analysis of a constraint-based model in a wide variety of molecular systems biology scenarios.
1 code implementation • 26 Apr 2012 • Alexander N. Gorban, Annick Harel-Bellan, Nadya Morozova, Andrei Zinovyev
Synthesis of proteins is one of the most fundamental biological processes, which consumes a significant amount of cellular resources.
Molecular Networks