no code implementations • 20 Dec 2021 • Subham Pal, Manmath Panigrahy, Arti Dua
Classical (deterministic) and single-enzyme (stochastic) description of the Michaelis-Menten (MM) kinetics, assume fast equilibration between enzyme and complex, and identify detailed balance as a sufficient condition for the hyperbolic substrate dependence of the MM equation (MME).
no code implementations • 2 Oct 2020 • Ashutosh Kumar, R. Adhikari, Arti Dua
We propose new statistical measures, defined in terms of turnover times, to distinguish between the transient and steady states and apply these to experimental data from a landmark experiment that first observed molecular memory in a single enzyme with multiple binding sites.
