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Estimating Probability Distributions using "Dirac" Kernels (via Rademacher-Walsh Polynomial Basis Functions)
In many applications (in particular information systems, such as pattern recognition, machine learning, cheminformatics, bioinformatics to name but a few) the assessment of uncertainty is essential - i. e., the estimation of the underlying probability distribution function.
Target Fishing: A Single-Label or Multi-Label Problem?
According to Cobanoglu et al and Murphy, it is now widely acknowledged that the single target paradigm (one protein or target, one disease, one drug) that has been the dominant premise in drug development in the recent past is untenable.
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