no code implementations • 11 Aug 2019 • Akos Vertes, Albert-Baskar Arul, Peter Avar, Andrew R. Korte, Lida Parvin, Ziad J. Sahab, Deborah I. Bunin, Merrill Knapp, Denise Nishita, Andrew Poggio, Mark-Oliver Stehr, Carolyn L. Talcott, Brian M. Davis, Christine A. Morton, Christopher J. Sevinsky, Maria I. Zavodszky
Transcriptomics response of SK-N-AS cells to methamidophos (an acetylcholine esterase inhibitor) exposure was measured at 10 time points between 0. 5 and 48 h. The data was analyzed using a combination of traditional statistical methods and novel machine learning algorithms for detecting anomalous behavior and infer causal relations between time profiles.
no code implementations • 6 May 2019 • Mark-Oliver Stehr, Peter Avar, Andrew R. Korte, Lida Parvin, Ziad J. Sahab, Deborah I. Bunin, Merrill Knapp, Denise Nishita, Andrew Poggio, Carolyn L. Talcott, Brian M. Davis, Christine A. Morton, Christopher J. Sevinsky, Maria I. Zavodszky, Akos Vertes
Our algorithms make different but overall relatively few biological assumptions, so that they are applicable to other types of biological data and potentially even to other complex systems that exhibit high dimensionality but are not of biological nature.