no code implementations • 25 Nov 2020 • Ellery Wulczyn, Kunal Nagpal, Matthew Symonds, Melissa Moran, Markus Plass, Robert Reihs, Farah Nader, Fraser Tan, Yuannan Cai, Trissia Brown, Isabelle Flament-Auvigne, Mahul B. Amin, Martin C. Stumpe, Heimo Muller, Peter Regitnig, Andreas Holzinger, Greg S. Corrado, Lily H. Peng, Po-Hsuan Cameron Chen, David F. Steiner, Kurt Zatloukal, Yun Liu, Craig H. Mermel
's C-indices were 0. 87 and 0. 85 for continuous and discrete grading, respectively, compared to 0. 79 (95%CI 0. 71-0. 86) for GG obtained from the reports.
no code implementations • 17 Nov 2020 • Ellery Wulczyn, David F. Steiner, Melissa Moran, Markus Plass, Robert Reihs, Fraser Tan, Isabelle Flament-Auvigne, Trissia Brown, Peter Regitnig, Po-Hsuan Cameron Chen, Narayan Hegde, Apaar Sadhwani, Robert MacDonald, Benny Ayalew, Greg S. Corrado, Lily H. Peng, Daniel Tse, Heimo Müller, Zhaoyang Xu, Yun Liu, Martin C. Stumpe, Kurt Zatloukal, Craig H. Mermel
Our approach can be used to explain predictions from a prognostic deep learning model and uncover potentially-novel prognostic features that can be reliably identified by people for future validation studies.
no code implementations • 16 Dec 2019 • Ellery Wulczyn, David F. Steiner, Zhaoyang Xu, Apaar Sadhwani, Hongwu Wang, Isabelle Flament, Craig H. Mermel, Po-Hsuan Cameron Chen, Yun Liu, Martin C. Stumpe
Our analysis demonstrates the potential for this approach to provide prognostic information in multiple cancer types, and even within specific pathologic stages.
no code implementations • 30 Jan 2019 • Narayan Hegde, Jason D. Hipp, Yun Liu, Michael E. Buck, Emily Reif, Daniel Smilkov, Michael Terry, Carrie J. Cai, Mahul B. Amin, Craig H. Mermel, Phil Q. Nelson, Lily H. Peng, Greg S. Corrado, Martin C. Stumpe
SMILY may be a useful general-purpose tool in the pathologist's arsenal, to improve the efficiency of searching large archives of histopathology images, without the need to develop and implement specific tools for each application.
no code implementations • 15 Jan 2019 • Timo Kohlberger, Yun Liu, Melissa Moran, Po-Hsuan, Chen, Trissia Brown, Craig H. Mermel, Jason D. Hipp, Martin C. Stumpe
OOF is often only detected upon careful review, potentially causing rescanning and workflow delays.
no code implementations • 15 Nov 2018 • Kunal Nagpal, Davis Foote, Yun Liu, Po-Hsuan, Chen, Ellery Wulczyn, Fraser Tan, Niels Olson, Jenny L. Smith, Arash Mohtashamian, James H. Wren, Greg S. Corrado, Robert MacDonald, Lily H. Peng, Mahul B. Amin, Andrew J. Evans, Ankur R. Sangoi, Craig H. Mermel, Jason D. Hipp, Martin C. Stumpe
For prostate cancer patients, the Gleason score is one of the most important prognostic factors, potentially determining treatment independent of the stage.