Search Results for author: Dawn L. DeMeo

Found 2 papers, 2 papers with code

DRAGON: Determining Regulatory Associations using Graphical models on multi-Omic Networks

1 code implementation4 Apr 2021 Katherine H. Shutta, Deborah Weighill, Rebekka Burkholz, Marouen Ben Guebila, Dawn L. DeMeo, Helena U. Zacharias, John Quackenbush, Michael Altenbuchinger

The increasing quantity of multi-omics data, such as methylomic and transcriptomic profiles, collected on the same specimen, or even on the same cell, provide a unique opportunity to explore the complex interactions that define cell phenotype and govern cellular responses to perturbations.

Function-on-Function Regression for the Identification of Epigenetic Regions Exhibiting Windows of Susceptibility to Environmental Exposures

2 code implementations13 Dec 2019 Michele Zemplenyi, Mark J. Meyer, Andres Cardenas, Marie-France Hivert, Sheryl L. Rifas-Shiman, Heike Gibson, Itai Kloog, Joel Schwartz, Emily Oken, Dawn L. DeMeo, Diane R. Gold, Brent A. Coull

The ability to identify time periods when individuals are most susceptible to exposures, as well as the biological mechanisms through which these exposures act, is of great public health interest.

Applications Methodology

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