no code implementations • 22 Dec 2023 • Jay Shenoy, Axel Levy, Frédéric Poitevin, Gordon Wetzstein
X-ray free-electron lasers (XFELs) offer unique capabilities for measuring the structure and dynamics of biomolecules, helping us understand the basic building blocks of life.
no code implementations • 17 Oct 2023 • David Klindt, Sophia Sanborn, Francisco Acosta, Frédéric Poitevin, Nina Miolane
Single neurons in neural networks are often interpretable in that they represent individual, intuitively meaningful features.
no code implementations • 12 Jun 2023 • Bongjin Koo, Julien Martel, Ariana Peck, Axel Levy, Frédéric Poitevin, Nina Miolane
Cryogenic electron microscopy (cryo-EM) has transformed structural biology by allowing to reconstruct 3D biomolecular structures up to near-atomic resolution.
no code implementations • 29 Sep 2022 • Youssef Nashed, Ariana Peck, Julien Martel, Axel Levy, Bongjin Koo, Gordon Wetzstein, Nina Miolane, Daniel Ratner, Frédéric Poitevin
Cryogenic electron microscopy (cryo-EM) provides a unique opportunity to study the structural heterogeneity of biomolecules.
1 code implementation • 15 Mar 2022 • Axel Levy, Frédéric Poitevin, Julien Martel, Youssef Nashed, Ariana Peck, Nina Miolane, Daniel Ratner, Mike Dunne, Gordon Wetzstein
We introduce cryoAI, an ab initio reconstruction algorithm for homogeneous conformations that uses direct gradient-based optimization of particle poses and the electron scattering potential from single-particle cryo-EM data.
no code implementations • 19 Nov 2019 • Nina Miolane, Frédéric Poitevin, Yee-Ting Li, Susan Holmes
As such, it opens the door to geometric approaches for unsupervised estimations of orientations and camera parameters, making possible fast cryo-EM biomolecule reconstruction.