DeepCRE: Transforming Drug R&D via AI-Driven Cross-drug Response Evaluation

no code implementations • 6 Mar 2024 • Ting Zhang, Hao Zhou, Hainan Wu, Hanwen Sunchu, Lei Hu, Xiaofang Chen, Suyuan Zhao, Gaochao liu, Chao Sun, Jiahuan Zhang, Yizhen Luo, Peng Liu, Zaiqing Nie, Yushuai Wu

The fields of therapeutic application and drug research and development (R&D) both face substantial challenges, i. e., the therapeutic domain calls for more treatment alternatives, while numerous promising pre-clinical drugs have failed in clinical trials.

DeepPicker: a Deep Learning Approach for Fully Automated Particle Picking in Cryo-EM

1 code implementation • 6 May 2016 • Feng Wang, Huichao Gong, Gaochao liu, Meijing Li, Chuangye Yan, Tian Xia, Xueming Li, Jianyang Zeng

Particle picking is a time-consuming step in single-particle analysis and often requires significant interventions from users, which has become a bottleneck for future automated electron cryo-microscopy (cryo-EM).

Single Particle Analysis