Substrates modulate charge-reorganization allosteric effects in protein-protein association

no code implementations • 11 Feb 2021 • Koyel Banerjee-Ghosh, Shirsendu Ghosh, Dorit Levy, Inbal Riven, Ron Naaman, Gilad Haran

Protein function may be modulated by an event occurring far away from the functional site, a phenomenon termed allostery.

Biological Physics Chemical Physics

The FRET-based structural dynamics challenge -- community contributions to consistent and open science practices

no code implementations • 4 Jun 2020 • Eitan Lerner, Benjamin Ambrose, Anders Barth, Victoria Birkedal, Scott C. Blanchard, Richard Borner, Thorben Cordes, Timothy D. Craggs, Taekjip Ha, Gilad Haran, Thorsten Hugel, Antonino Ingargiola, Achillefs Kapanidis, Don C. Lamb, Ted Laurence, Nam ki Lee, Edward A. Lemke, Emmanuel Margeat, Jens Michaelis, Xavier Michalet, Daniel Nettels, Thomas-Otavio Peulen, Benjamin Schuler, Claus A. M. Seidel, Hamid So-leimaninejad, Shimon Weiss

These recent efforts include multi-lab blind-tests to assess the accuracy and precision of smFRET between different labs using different procedures, the formal assembly of the FRET community and development of smFRET procedures to be considered for entries in the wwPDB.

Position