1 code implementation • 29 Aug 2020 • Marta Bofill Roig, Yu Shen, Guadalupe Gómez Melis
We propose to base the comparison between arms on the difference of the restricted mean survival times, and show how the effect size and sample size for overall survival rely on the probability of the binary response and the survival distribution by response status, both for each treatment arm.
Methodology Applications
1 code implementation • 4 Feb 2020 • Marta Bofill Roig, Guadalupe Gómez Melis
We propose a class of two-sample statistics for testing the equality of proportions and the equality of survival functions.
Methodology Applications
2 code implementations • 3 Jul 2018 • Marta Bofill Roig, Guadalupe Gómez Melis
As shown in this work, when using a composite binary endpoint to size a trial, one needs to specify the event rates and the effect sizes of the composite components as well as the correlation between them.
Applications
