Search Results for author: Guillermo Lorenzo

Found 5 papers, 0 papers with code

Patient-specific, mechanistic models of tumor growth incorporating artificial intelligence and big data

no code implementations28 Aug 2023 Guillermo Lorenzo, Syed Rakin Ahmed, David A. Hormuth II, Brenna Vaughn, Jayashree Kalpathy-Cramer, Luis Solorio, Thomas E. Yankeelov, Hector Gomez

Despite the remarkable advances in cancer diagnosis, treatment, and management that have occurred over the past decade, malignant tumors remain a major public health problem.

Identifying mechanisms driving the early response of triple negative breast cancer patients to neoadjuvant chemotherapy using a mechanistic model integrating in vitro and in vivo imaging data

no code implementations8 Dec 2022 Guillermo Lorenzo, Angela M. Jarrett, Christian T. Meyer, Vito Quaranta, Darren R. Tyson, Thomas E. Yankeelov

As longitudinal \textsl{in vivo} MRI data for model calibration is limited, we perform a sensitivity analysis to identify the model mechanisms driving the response to two NAC drug combinations: doxorubicin with cyclophosphamide, and paclitaxel with carboplatin.

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