The Coming of Age of Nucleic Acid Vaccines during COVID-19

1 code implementation • 14 Oct 2022 • Halie M. Rando, Ronan Lordan, Likhitha Kolla, Elizabeth Sell, Alexandra J. Lee, Nils Wellhausen, Amruta Naik, Jeremy P. Kamil, COVID-19 Review Consortium, Anthony Gitter, Casey S. Greene

During the COVID-19 pandemic, these DNA and RNA vaccines have facilitated the development and deployment of vaccines at an unprecedented pace.

Application of Traditional Vaccine Development Strategies to SARS-CoV-2

no code implementations • 16 Aug 2022 • Halie M. Rando, Ronan Lordan, Alexandra J. Lee, Amruta Naik, Nils Wellhausen, Elizabeth Sell, Likhitha Kolla, COVID-19 Review Consortium, Anthony Gitter, Casey S. Greene

Subunit vaccines contain instead an isolated, immunogenic component of the virus.

Management

Molecular and Serologic Diagnostic Technologies for SARS-CoV-2

no code implementations • 26 Apr 2022 • Halie M. Rando, Christian Brueffer, Ronan Lordan, Anna Ada Dattoli, David Manheim, Jesse G. Meyer, Ariel I. Mundo, Dimitri Perrin, David Mai, Nils Wellhausen, COVID-19 Review Consortium, Anthony Gitter, Casey S. Greene

These two categories of tests provide different perspectives valuable to understanding the spread of SARS-CoV-2.

Identification and Development of Therapeutics for COVID-19

no code implementations • 3 Mar 2021 • Halie M. Rando, Nils Wellhausen, Soumita Ghosh, Alexandra J. Lee, Anna Ada Dattoli, Fengling Hu, James Brian Byrd, Diane N. Rafizadeh, Ronan Lordan, Yanjun Qi, Yuchen Sun, Christian Brueffer, Jeffrey M. Field, Marouen Ben Guebila, Nafisa M. Jadavji, Ashwin N. Skelly, Bharath Ramsundar, Jinhui Wang, Rishi Raj Goel, YoSon Park, the COVID-19 Review Consortium, Simina M. Boca, Anthony Gitter, Casey S. Greene

A number of potential therapeutics against SARS-CoV-2 and the resultant COVID-19 illness were rapidly identified, leading to a large number of clinical trials investigating a variety of possible therapeutic approaches being initiated early on in the pandemic.

Dietary Supplements and Nutraceuticals Under Investigation for COVID-19 Prevention and Treatment

no code implementations • 3 Feb 2021 • Ronan Lordan, Halie M. Rando, COVID-19 Review Consortium, Casey S. Greene

Coronavirus disease 2019 (COVID-19) has caused global disruption and a significant loss of life.

Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure

1 code implementation • 1 Feb 2021 • Halie M. Rando, Adam L. MacLean, Alexandra J. Lee, Ronan Lordan, Sandipan Ray, Vikas Bansal, Ashwin N. Skelly, Elizabeth Sell, John J. Dziak, Lamonica Shinholster, Lucy D'Agostino McGowan, Marouen Ben Guebila, Nils Wellhausen, Sergey Knyazev, Simina M. Boca, Stephen Capone, Yanjun Qi, YoSon Park, Yuchen Sun, David Mai, Joel D. Boerckel, Christian Brueffer, James Brian Byrd, Jeremy P. Kamil, Jinhui Wang, Ryan Velazquez, Gregory L Szeto, John P. Barton, Rishi Raj Goel, Serghei Mangul, Tiago Lubiana, COVID-19 Review Consortium, Anthony Gitter, Casey S. Greene

While this viral species was unknown prior to January 2020, its similarity to other coronaviruses that infect humans has allowed for rapid insight into the mechanisms that it uses to infect human hosts, as well as the ways in which the human immune system can respond.