1 code implementation • 30 Nov 2021 • Sen Wang, Hengchao Wang, Fan Jiang, Anqi Wang, Hangwei Liu, Hanbo Zhao, Boyuan Yang, Dong Xu, Yan Zhang, Wei Fan
As the Hi-C links of two adjacent contigs concentrate only at the neighbor ends of the contigs, larger contig size will reduce the power to differentiate adjacent (signal) and non-adjacent (noise) contig linkages, leading to a higher rate of mis-assembly.
1 code implementation • 26 Mar 2020 • Hengchao Wang, Bo Liu, Yan Zhang, Fan Jiang, Yuwei Ren, Lijuan Yin, Hangwei Liu, Sen Wang, Wei Fan
We show that corrected third-generation data can be used to count k-mer frequencies and estimate genome size reliably, in replacement of using second-generation data.
