no code implementations • 12 Oct 2023 • Chen Zhao, Kuan-Jui Su, Chong Wu, Xuewei Cao, Qiuying Sha, Wu Li, Zhe Luo, Tian Qin, Chuan Qiu, Lan Juan Zhao, Anqi Liu, Lindong Jiang, Xiao Zhang, Hui Shen, Weihua Zhou, Hong-Wen Deng
By learning the latent representations of both omics data, our method can effectively impute missing metabolomics values based on genomic information.
1 code implementation • 15 Aug 2023 • Anton Orlichenko, Kuan-Jui Su, Qing Tian, Hui Shen, Hong-Wen Deng, Yu-Ping Wang
Using the full FC and a training set of 2, 000 subjects, one is able to predict which scan is older 82. 5\% of the time using either the full Power264 FC or the UKB-provided ICA-based FC.
1 code implementation • 2 Aug 2023 • Anton Orlichenko, Gang Qu, Kuan-Jui Su, Anqi Liu, Hui Shen, Hong-Wen Deng, Yu-Ping Wang
Using the UK Biobank dataset, we find one can achieve the same level of variance explained with 50 training subjects by exploiting identifiability as with 10, 000 training subjects without double-dipping.
no code implementations • 12 Apr 2023 • Chen Zhao, Anqi Liu, Xiao Zhang, Xuewei Cao, Zhengming Ding, Qiuying Sha, Hui Shen, Hong-Wen Deng, Weihua Zhou
Integration of heterogeneous and high-dimensional multi-omics data is becoming increasingly important in understanding genetic data.
no code implementations • 1 Feb 2023 • Anton Orlichenko, Grant Daly, Ziyu Zhou, Anqi Liu, Hui Shen, Hong-Wen Deng, Yu-Ping Wang
The reason is that it is too slow and cumbersome to use a programming interface to create all the necessary visualizations required to identify all correlations, confounding effects, or quality control problems in a dataset.
no code implementations • 3 Oct 2022 • Xuewei Cao, Joyce H Keyak, Sigurdur Sigurdsson, Chen Zhao, Weihua Zhou, Anqi Liu, Thomas Lang, Hong-Wen Deng, Vilmundur Gudnason, Qiuying Sha
The results showed that the average of the area under the receive operating characteristic curve (AUC) using PC1 was always higher than that using all FE parameters combined in the male subjects.
no code implementations • 3 Oct 2022 • Chen Zhao, Joyce H Keyak, Xuewei Cao, Qiuying Sha, Li Wu, Zhe Luo, LanJuan Zhao, Qing Tian, Chuan Qiu, Ray Su, Hui Shen, Hong-Wen Deng, Weihua Zhou
The aim of this paper is to design a deep learning-based model to predict proximal femoral strength using multi-view information fusion.
no code implementations • 13 Jan 2022 • Md ashad Alam, Hui Shen, Hong-Wen Deng
Many statistical machine approaches could ultimately highlight novel features of the etiology of complex diseases by analyzing multi-omics data.
no code implementations • 3 Feb 2021 • Yu Deng, Ling Wang, Chen Zhao, Shaojie Tang, Xiaoguang Cheng, Hong-Wen Deng, Weihua Zhou
In this study, we proposed an approach based on deep learning for the automatic extraction of the periosteal and endosteal contours of proximal femur in order to differentiate cortical and trabecular bone compartments.
no code implementations • 25 Jan 2021 • Chen Zhao, Haipeng Tang, Daniel McGonigle, Zhuo He, Chaoyang Zhang, Yu-Ping Wang, Hong-Wen Deng, Robert Bober, Weihua Zhou
We aim to develop an automatic algorithm by deep learning to extract coronary arteries from ICAs. In this study, a multi-input and multi-scale (MIMS) U-Net with a two-stage recurrent training strategy was proposed for the automatic vessel segmentation.
no code implementations • 9 Jun 2020 • Chen Zhao, Joyce H. Keyak, Jinshan Tang, Tadashi S. Kaneko, Sundeep Khosla, Shreyasee Amin, Elizabeth J. Atkinson, Lan-Juan Zhao, Michael J. Serou, Chaoyang Zhang, Hui Shen, Hong-Wen Deng, Weihua Zhou
During the experiments for the entire cohort then for male and female subjects separately, 90% of the subjects were used in 10-fold cross-validation for training and internal validation, and to select the optimal parameters of the proposed models; the rest of the subjects were used to evaluate the performance of models.
no code implementations • 29 Apr 2020 • Md. Ashad Alam, Chuan Qiu, Hui Shen, Yu-Ping Wang, Hong-Wen Deng
In this paper, we propose a novel generalized kernel machine approach to identify higher-order composite effects in multi-view biomedical datasets.