Search Results for author: Hongda Wang

Found 10 papers, 1 papers with code

Rapid and stain-free quantification of viral plaque via lens-free holography and deep learning

no code implementations30 Jun 2022 Tairan Liu, Yuzhu Li, Hatice Ceylan Koydemir, Yijie Zhang, Ethan Yang, Merve Eryilmaz, Hongda Wang, Jingxi Li, Bijie Bai, Guangdong Ma, Aydogan Ozcan

We also demonstrated that this data-driven plaque assay offers the capability of quantifying the infected area of the cell monolayer, performing automated counting and quantification of PFUs and virus-infected areas over a 10-fold larger dynamic range of virus concentration than standard viral plaque assays.

Specificity Virology

Deep Learning-enabled Detection and Classification of Bacterial Colonies using a Thin Film Transistor (TFT) Image Sensor

no code implementations7 May 2022 Yuzhu Li, Tairan Liu, Hatice Ceylan Koydemir, Hongda Wang, Keelan O'Riordan, Bijie Bai, Yuta Haga, Junji Kobashi, Hitoshi Tanaka, Takaya Tamaru, Kazunori Yamaguchi, Aydogan Ozcan

Due to the large scalability, ultra-large field-of-view, and low cost of the TFT-based image sensors, this platform can be integrated with each agar plate to be tested and disposed of after the automated CFU count.

Cultural Vocal Bursts Intensity Prediction

Label-free virtual HER2 immunohistochemical staining of breast tissue using deep learning

no code implementations8 Dec 2021 Bijie Bai, Hongda Wang, Yuzhu Li, Kevin De Haan, Francesco Colonnese, Yujie Wan, Jingyi Zuo, Ngan B. Doan, Xiaoran Zhang, Yijie Zhang, Jingxi Li, Wenjie Dong, Morgan Angus Darrow, Elham Kamangar, Han Sung Lee, Yair Rivenson, Aydogan Ozcan

The immunohistochemical (IHC) staining of the human epidermal growth factor receptor 2 (HER2) biomarker is widely practiced in breast tissue analysis, preclinical studies and diagnostic decisions, guiding cancer treatment and investigation of pathogenesis.

Generative Adversarial Network whole slide images

Deep learning-based virtual refocusing of images using an engineered point-spread function

no code implementations22 Dec 2020 Xilin Yang, Luzhe Huang, Yilin Luo, Yichen Wu, Hongda Wang, Yair Rivenson, Aydogan Ozcan

We present a virtual image refocusing method over an extended depth of field (DOF) enabled by cascaded neural networks and a double-helix point-spread function (DH-PSF).

Image Reconstruction

Deep learning-based holographic polarization microscopy

no code implementations1 Jul 2020 Tairan Liu, Kevin de Haan, Bijie Bai, Yair Rivenson, Yi Luo, Hongda Wang, David Karalli, Hongxiang Fu, Yibo Zhang, John FitzGerald, Aydogan Ozcan

Our analysis shows that a trained deep neural network can extract the birefringence information using both the sample specific morphological features as well as the holographic amplitude and phase distribution.

Medical Diagnosis

Early-detection and classification of live bacteria using time-lapse coherent imaging and deep learning

no code implementations29 Jan 2020 Hongda Wang, Hatice Ceylan Koydemir, Yunzhe Qiu, Bijie Bai, Yibo Zhang, Yiyin Jin, Sabiha Tok, Enis Cagatay Yilmaz, Esin Gumustekin, Yair Rivenson, Aydogan Ozcan

Our experiments further confirmed that this method successfully detects 90% of bacterial colonies within 7-10 h (and >95% within 12 h) with a precision of 99. 2-100%, and correctly identifies their species in 7. 6-12 h with 80% accuracy.

Cultural Vocal Bursts Intensity Prediction General Classification

Three-dimensional virtual refocusing of fluorescence microscopy images using deep learning

1 code implementation31 Jan 2019 Yichen Wu, Yair Rivenson, Hongda Wang, Yilin Luo, Eyal Ben-David, Laurent A. Bentolila, Christian Pritz, Aydogan Ozcan

Three-dimensional (3D) fluorescence microscopy in general requires axial scanning to capture images of a sample at different planes.

Deep learning-based virtual histology staining using auto-fluorescence of label-free tissue

no code implementations30 Mar 2018 Yair Rivenson, Hongda Wang, Zhensong Wei, Yibo Zhang, Harun Gunaydin, Aydogan Ozcan

Here, we demonstrate a label-free approach to create a virtually-stained microscopic image using a single wide-field auto-fluorescence image of an unlabeled tissue sample, bypassing the standard histochemical staining process, saving time and cost.

Generative Adversarial Network

Deep learning enhanced mobile-phone microscopy

no code implementations12 Dec 2017 Yair Rivenson, Hatice Ceylan Koydemir, Hongda Wang, Zhensong Wei, Zhengshuang Ren, Harun Gunaydin, Yibo Zhang, Zoltan Gorocs, Kyle Liang, Derek Tseng, Aydogan Ozcan

Mobile-phones have facilitated the creation of field-portable, cost-effective imaging and sensing technologies that approach laboratory-grade instrument performance.

Deep Learning Microscopy

no code implementations12 May 2017 Yair Rivenson, Zoltan Gorocs, Harun Gunaydin, Yibo Zhang, Hongda Wang, Aydogan Ozcan

We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field.

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