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A continuum model for the unfolding of von Willebrand Factor
vWF unfolding takes place via two regimes: tumbling in simple shear and strong unfolding in flows with dominant extensional component.
Uncertainty quantification of a thrombosis model considering the clotting assay PFA-100
The analysis is performed using a polynomial chaos expansion as a parametric surrogate for the thrombosis model.
Synergistic effect of shear and ADP on platelet growth on ZTA and Ti6Al4V surfaces
Additionally, we observed embolization when thrombus areas exceeded 300{\mu}m2, which was dependent on the combination of shear, ADP concentration, and material surface.
Influence of shear rate and surface chemistry on thrombus formation in micro-crevice
Thromboembolic complications remain a central issue in management of patients on mechanical circulatory support.
Limitations of ROC on Imbalanced Data: Evaluation of LVAD Mortality Risk Scores
Methods: This study compared the ROC and PRC for the outcome of two classifiers for 90-day LVAD mortality for 800 patients (test group) recorded in INTERMACS who received a continuous-flow LVAD between 2006 and 2016 (mean age of 59 years; 146 females vs. 654 males) in which mortality rate is only %8 at 90-day (imbalanced data).
