Search Results for author: James Lu

Found 7 papers, 2 papers with code

Integration of Graph Neural Network and Neural-ODEs for Tumor Dynamic Prediction

no code implementations2 Oct 2023 Omid Bazgir, Zichen Wang, Ji Won Park, Marc Hafner, James Lu

Additionally, we show that the graph encoder is able to effectively utilize multimodal data to enhance tumor predictions.

Explainable Deep Learning for Tumor Dynamic Modeling and Overall Survival Prediction using Neural-ODE

1 code implementation2 Aug 2023 Mark Laurie, James Lu

We propose the use of Tumor Dynamic Neural-ODE (TDNODE) as a pharmacology-informed neural network to enable model discovery from longitudinal tumor size data.

Decision Making Model Discovery +1

Computing the Hazard Ratios Associated with Explanatory Variables Using Machine Learning Models of Survival Data

1 code implementation1 Feb 2021 Sameer Sundrani, James Lu

In the pan-cancer dataset, we showed agreement in most variables but also an opposite finding in two of the explanatory variables between the CoxPH and XGBoost result.

BIG-bench Machine Learning Survival Analysis

Deep learning prediction of patient response time course from early data via neural-pharmacokinetic/pharmacodynamic modeling

no code implementations22 Oct 2020 James Lu, Brendan Bender, Jin Y. Jin, Yuanfang Guan

The longitudinal analysis of patient response time course following doses of therapeutics is currently performed using Pharmacokinetic/Pharmacodynamic (PK/PD) methodologies, which requires significant human experience and expertise in the modeling of dynamical systems.

Deep Poisson Factor Modeling

no code implementations NeurIPS 2015 Ricardo Henao, Zhe Gan, James Lu, Lawrence Carin

We propose a new deep architecture for topic modeling, based on Poisson Factor Analysis (PFA) modules.

Topic Models

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