no code implementations • 20 Jul 2016 • Jenna Reps, Zhaoyang Guo, Haoyue Zhu, Uwe Aickelin
Big longitudinal observational databases present the opportunity to extract new knowledge in a cost effective manner.
no code implementations • 24 Feb 2015 • Jenna Reps, Uwe Aickelin, Jonathan Garibaldi, Chris Damski
The results showed there were clear differences in the way the profiles interact with the different advert genres and the results of this paper suggest that mobile advert targeting would improve the frequency that users interact with an advert.
no code implementations • 3 Sep 2014 • Jenna Reps, Jonathan M. Garibaldi, Uwe Aickelin, Daniele Soria, Jack E. Gibson, Richard B. Hubbard
In this paper we investigate potential attributes that can be used in causal inference to identify side effects based on the Bradford-Hill causality criteria.
no code implementations • 2 Sep 2014 • Jenna Reps, Jonathan M. Garibaldi, Uwe Aickelin, Daniele Soria, Jack E. Gibson, Richard B. Hubbard
Drugs are frequently prescribed to patients with the aim of improving each patient's medical state, but an unfortunate consequence of most prescription drugs is the occurrence of undesirable side effects.
no code implementations • 2 Sep 2014 • Jenna Reps, Jonathan M. Garibaldi, Uwe Aickelin, Daniele Soria, Jack Gibson, Richard Hubbard
In this paper we apply four existing electronic healthcare database signal detecting algorithms (MUTARA, HUNT, Temporal Pattern Discovery and modified ROR) on the THIN database for a selection of drugs from six chosen drug families.
no code implementations • 5 Jul 2013 • Jenna Reps, Jonathan M. Garibaldi, Uwe Aickelin, Daniele Soria, Jack E. Gibson, Richard B. Hubbard
Longitudinal observational databases have become a recent interest in the post marketing drug surveillance community due to their ability of presenting a new perspective for detecting negative side effects.
no code implementations • 4 Jul 2013 • Jenna Reps, Jonathan M. Garibaldi, Uwe Aickelin, Daniele Soria, Jack E. Gibson, Richard B. Hubbard
The wealth of computerised medical information becoming readily available presents the opportunity to examine patterns of illnesses, therapies and responses.
no code implementations • 4 Jul 2013 • Feng Gu, Jan Feyereisl, Robert Oates, Jenna Reps, Julie Greensmith, Uwe Aickelin
It is found that this feature, while advantageous for noisy, time-ordered classification, is not as useful as a traditional static filter for processing a synthetic dataset.
no code implementations • 3 Jul 2013 • Jenna Reps, Jan Feyereisl, Jonathan M. Garibaldi, Uwe Aickelin, Jack E. Gibson, Richard B. Hubbard
In this paper, existing methods developed for spontaneous reporting databases are implemented on both a spontaneous reporting database and a general practice electronic health-care database and compared.