Search Results for author: Jonathan Desponds

Found 2 papers, 1 papers with code

Early life imprints the hierarchy of T cell clone sizes

1 code implementation21 Jul 2020 Mario U. Gaimann, Maximilian Nguyen, Jonathan Desponds, Andreas Mayer

The adaptive immune system responds to pathogens by selecting clones of cells with specific receptors.

Human Aging

Receptor crosstalk improves concentration sensing of multiple ligands

no code implementations10 Oct 2018 Martin Carballo-Pacheco, Jonathan Desponds, Tatyana Gavrilchenko, Andreas Mayer, Roshan Prizak, Gautam Reddy, Ilya Nemenman, Thierry Mora

Crosstalk is often thought of as a deviation from optimal specific recognition, as the binding of non-cognate ligands can interfere with the detection of the receptor's cognate ligand, possibly leading to a false triggering of a downstream signaling pathway.

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