Search Results for author: Julien Martel

Found 7 papers, 4 papers with code

CryoChains: Heterogeneous Reconstruction of Molecular Assembly of Semi-flexible Chains from Cryo-EM Images

no code implementations12 Jun 2023 Bongjin Koo, Julien Martel, Ariana Peck, Axel Levy, Frédéric Poitevin, Nina Miolane

Cryogenic electron microscopy (cryo-EM) has transformed structural biology by allowing to reconstruct 3D biomolecular structures up to near-atomic resolution.

3D Reconstruction Cryogenic Electron Microscopy (cryo-EM)

Towards Trustworthy Automatic Diagnosis Systems by Emulating Doctors' Reasoning with Deep Reinforcement Learning

1 code implementation13 Oct 2022 Arsene Fansi Tchango, Rishab Goel, Julien Martel, Zhi Wen, Gaetan Marceau Caron, Joumana Ghosn

In their initial interaction with patients, doctors do not only focus on identifying the pathology a patient is suffering from; they instead generate a differential diagnosis (in the form of a short list of plausible diseases) because the medical evidence collected from patients is often insufficient to establish a final diagnosis.

Reinforcement Learning (RL)

Amortized Inference for Heterogeneous Reconstruction in Cryo-EM

no code implementations13 Oct 2022 Axel Levy, Gordon Wetzstein, Julien Martel, Frederic Poitevin, Ellen D. Zhong

Cryo-electron microscopy (cryo-EM) is an imaging modality that provides unique insights into the dynamics of proteins and other building blocks of life.

DDXPlus: A New Dataset For Automatic Medical Diagnosis

1 code implementation18 May 2022 Arsene Fansi Tchango, Rishab Goel, Zhi Wen, Julien Martel, Joumana Ghosn

In this work, we present a large-scale synthetic dataset of roughly 1. 3 million patients that includes a differential diagnosis, along with the ground truth pathology, symptoms and antecedents for each patient.

Medical Diagnosis

CryoAI: Amortized Inference of Poses for Ab Initio Reconstruction of 3D Molecular Volumes from Real Cryo-EM Images

1 code implementation15 Mar 2022 Axel Levy, Frédéric Poitevin, Julien Martel, Youssef Nashed, Ariana Peck, Nina Miolane, Daniel Ratner, Mike Dunne, Gordon Wetzstein

We introduce cryoAI, an ab initio reconstruction algorithm for homogeneous conformations that uses direct gradient-based optimization of particle poses and the electron scattering potential from single-particle cryo-EM data.

Computational Efficiency

Kernelized Synaptic Weight Matrices

2 code implementations ICML 2018 Lorenz Muller, Julien Martel, Giacomo Indiveri

In this paper we introduce a novel neural network architecture, in which weight matrices are re-parametrized in terms of low-dimensional vectors, interacting through kernel functions.

Collaborative Filtering Data Visualization +1

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