Search Results for author: Kevin L. Keys

Found 3 papers, 3 papers with code

Iterative Hard Thresholding for Model Selection in Genome-Wide Association Studies

1 code implementation4 Aug 2016 Kevin L. Keys, Gary K. Chen, Kenneth Lange

This paper introduces the iterative hard thresholding (IHT) algorithm to the GWAS analysis of continuous traits.

Model Selection regression

Proximal Distance Algorithms: Theory and Examples

1 code implementation19 Apr 2016 Kevin L. Keys, Hua Zhou, Kenneth Lange

If $f(\boldsymbol{x})$ is the loss function, and $C$ is the constraint set in a constrained minimization problem, then the proximal distance principle mandates minimizing the penalized loss $f(\boldsymbol{x})+\frac{\rho}{2}\mathop{dist}(x, C)^2$ and following the solution $\boldsymbol{x}_{\rho}$ to its limit as $\rho$ tends to $\infty$.

Optimization and Control 90C59, 90C26, 65K05

The proximal distance algorithm

1 code implementation27 Jul 2015 Kenneth Lange, Kevin L. Keys

For convex programming subject to nonsmooth constraints, one can combine an exact penalty method with distance majorization to create versatile algorithms that are effective even in discrete optimization.

Optimization and Control Data Structures and Algorithms

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