1 code implementation • 29 Mar 2023 • Thomas Parmer, Luis M. Rocha
We present a novel algorithm to automatically extract pathway modules from networks and we characterize the interactions that may take place between modules.
no code implementations • 19 Jan 2022 • Ian B. Wood, Rion Brattig Correia, Wendy R. Miller, Luis M. Rocha
Sudden Unexpected Death in Epilepsy (SUDEP) remains a leading cause of death in people with epilepsy.
no code implementations • 20 Oct 2021 • Luis M. Rocha
A recent article by Weidner et al. [2021] presents a method to extract graph properties that are predictive of the dynamical behavior of multivariate, discrete models of biochemical regulation.
1 code implementation • 8 Mar 2021 • Tiago Simas, Rion Brattig Correia, Luis M. Rocha
Redundancy needs more precise characterization as it is a major factor in the evolution and robustness of networks of multivariate interactions.
no code implementations • 20 Jan 2021 • Santosh Manicka, Manuel Marques-Pita, Luis M. Rocha
This parsimony in the number of parameters needed sometimes leads to uncertain predictions about the dynamical regime of both random and systems biology models of biochemical regulation.
1 code implementation • 9 Mar 2018 • Rion Brattig Correia, Luciana P. de Araújo, Mauro M. Mattos, Luis M. Rocha
The occurrence of drug-drug-interactions (DDI) from multiple drug dispensations is a serious problem, both for individuals and health-care systems, since patients with complications due to DDI are likely to reenter the system at a costlier level.
no code implementations • 5 Oct 2015 • Rion Brattig Correia, Lang Li, Luis M. Rocha
This demonstrates that Instagram contains much drug- and pathology specific data for public health monitoring of DDI and ADR, and that complex network analysis provides an important toolbox to extract health-related associations and their support from large-scale social media data.
1 code implementation • 15 Sep 2015 • Artemy Kolchinsky, Alexander J. Gates, Luis M. Rocha
We propose a method to decompose dynamical systems based on the idea that modules constrain the spread of perturbations.
Physics and Society Social and Information Networks Adaptation and Self-Organizing Systems Data Analysis, Statistics and Probability
no code implementations • 2 Dec 2014 • Artemy Kolchinsky, Anália Lourenço, Heng-Yi Wu, Lang Li, Luis M. Rocha
We used manually curated corpora of PubMed abstracts and annotated sentences to evaluate the efficacy of literature mining on two tasks: first, identifying PubMed abstracts containing pharmacokinetic evidence of DDIs; second, extracting sentences containing such evidence from abstracts.
no code implementations • 19 Jun 2011 • Artemy Kolchinsky, Luis M. Rocha
Identifying and understanding modular organizations is centrally important in the study of complex systems.