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Found 4 papers, 1 papers with code
Competition for binding targets results in paradoxical effects for simultaneous activator and repressor action -- Extended Version
The paper first reviews the motivating cancer biology work, and then describes a proposed synthetic construct.
Epigenetic factor competition reshapes the EMT landscape
In such models, epigenetic factors are usually proposed to act on the chromatin regions directly involved in the expression of relevant genes.
Mediating Ribosomal Competition by Splitting Pools
The competition for resources between host and circuit genes can be ameliorated by splitting the ribosome pool by use of orthogonal ribosomes, where the circuit genes are exclusively translated by mutated ribosomes.
Analysis of a reduced model of epithelial-mesenchymal fate determination in cancer metastasis as a singularly-perturbed monotone system
Tumor metastasis is one of the main factors responsible for the high fatality rate of cancer.
