no code implementations • 29 Dec 2023 • Miloš Nikolić, Victoria Antonetti, Feng Liu, Gentian Muhaxheri, Mariela D. Petkova, Martin Scheeler, Eric M. Smith, William Bialek, Thomas Gregor
The body plan of the fruit fly is determined by the expression of just a handful of genes.
no code implementations • 10 Dec 2023 • Lauren McGough, Helena Casademunt, Miloš Nikolić, Mariela D. Petkova, Thomas Gregor, William Bialek
In a developing embryo, information about the position of cells is encoded in the concentrations of "morphogen" molecules.
1 code implementation • 13 Jul 2021 • Zudi Lin, Donglai Wei, Mariela D. Petkova, Yuelong Wu, Zergham Ahmed, Krishna Swaroop K, Silin Zou, Nils Wendt, Jonathan Boulanger-Weill, Xueying Wang, Nagaraju Dhanyasi, Ignacio Arganda-Carreras, Florian Engert, Jeff Lichtman, Hanspeter Pfister
Segmenting 3D cell nuclei from microscopy image volumes is critical for biological and clinical analysis, enabling the study of cellular expression patterns and cell lineages.
no code implementations • 31 Dec 2020 • Marianne Bauer, Mariela D. Petkova, Thomas Gregor, Eric F. Wieschaus, William Bialek
We argue that cells in the embryo can extract all the available information about their position, but only if the concentration measurements approach the physical limits to information capacity.
no code implementations • 23 Jul 2018 • Jingxiang Shen, Mariela D. Petkova, Yuhai Tu, Feng Liu, Chao Tang
Furthermore, the regulation network it uncovers is strikingly similar to the one inferred from experiments.