Search Results for author: Melanie F. Pradier

Found 11 papers, 2 papers with code

AIRIVA: A Deep Generative Model of Adaptive Immune Repertoires

no code implementations26 Apr 2023 Melanie F. Pradier, Niranjani Prasad, Paidamoyo Chapfuwa, Sahra Ghalebikesabi, Max Ilse, Steven Woodhouse, Rebecca Elyanow, Javier Zazo, Javier Gonzalez, Julia Greissl, Edward Meeds

Recent advances in immunomics have shown that T-cell receptor (TCR) signatures can accurately predict active or recent infection by leveraging the high specificity of TCR binding to disease antigens.

Specificity

Repairing Neural Networks by Leaving the Right Past Behind

no code implementations11 Jul 2022 Ryutaro Tanno, Melanie F. Pradier, Aditya Nori, Yingzhen Li

Prediction failures of machine learning models often arise from deficiencies in training data, such as incorrect labels, outliers, and selection biases.

Continual Learning

Preferential Mixture-of-Experts: Interpretable Models that Rely on Human Expertise as much as Possible

no code implementations13 Jan 2021 Melanie F. Pradier, Javier Zazo, Sonali Parbhoo, Roy H. Perlis, Maurizio Zazzi, Finale Doshi-Velez

We propose Preferential MoE, a novel human-ML mixture-of-experts model that augments human expertise in decision making with a data-based classifier only when necessary for predictive performance.

Decision Making Management

Towards Expressive Priors for Bayesian Neural Networks: Poisson Process Radial Basis Function Networks

no code implementations12 Dec 2019 Beau Coker, Melanie F. Pradier, Finale Doshi-Velez

While Bayesian neural networks have many appealing characteristics, current priors do not easily allow users to specify basic properties such as expected lengthscale or amplitude variance.

regression

Challenges in Computing and Optimizing Upper Bounds of Marginal Likelihood based on Chi-Square Divergences

no code implementations pproximateinference AABI Symposium 2019 Melanie F. Pradier, Michael C. Hughes, Finale Doshi-Velez

Variational inference based on chi-square divergence minimization (CHIVI) provides a way to approximate a model's posterior while obtaining an upper bound on the marginal likelihood.

Variational Inference

Output-Constrained Bayesian Neural Networks

1 code implementation15 May 2019 Wanqian Yang, Lars Lorch, Moritz A. Graule, Srivatsan Srinivasan, Anirudh Suresh, Jiayu Yao, Melanie F. Pradier, Finale Doshi-Velez

Bayesian neural network (BNN) priors are defined in parameter space, making it hard to encode prior knowledge expressed in function space.

Unsupervised Extraction of Phenotypes from Cancer Clinical Notes for Association Studies

no code implementations29 Apr 2019 Stefan G. Stark, Stephanie L. Hyland, Melanie F. Pradier, Kjong Lehmann, Andreas Wicki, Fernando Perez Cruz, Julia E. Vogt, Gunnar Rätsch

To demonstrate the utility of our approach, we perform an association study of clinical features with somatic mutation profiles from 4, 007 cancer patients and their tumors.

Clustering

Projected BNNs: Avoiding weight-space pathologies by learning latent representations of neural network weights

no code implementations16 Nov 2018 Melanie F. Pradier, Weiwei Pan, Jiayu Yao, Soumya Ghosh, Finale Doshi-Velez

As machine learning systems get widely adopted for high-stake decisions, quantifying uncertainty over predictions becomes crucial.

Variational Inference

Sparse Three-parameter Restricted Indian Buffet Process for Understanding International Trade

no code implementations29 Jun 2018 Melanie F. Pradier, Viktor Stojkoski, Zoran Utkovski, Ljupco Kocarev, Fernando Perez-Cruz

This paper presents a Bayesian nonparametric latent feature model specially suitable for exploratory analysis of high-dimensional count data.

General Latent Feature Modeling for Data Exploration Tasks

no code implementations26 Jul 2017 Isabel Valera, Melanie F. Pradier, Zoubin Ghahramani

This paper introduces a general Bayesian non- parametric latent feature model suitable to per- form automatic exploratory analysis of heterogeneous datasets, where the attributes describing each object can be either discrete, continuous or mixed variables.

General Latent Feature Models for Heterogeneous Datasets

1 code implementation12 Jun 2017 Isabel Valera, Melanie F. Pradier, Maria Lomeli, Zoubin Ghahramani

Second, its Bayesian nonparametric nature allows us to automatically infer the model complexity from the data, i. e., the number of features necessary to capture the latent structure in the data.

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