Search Results for author: Michael Habeck

Found 9 papers, 3 papers with code

CowScape: Quantitative reconstruction of the conformational landscape of biological macromolecules from cryo-EM data

no code implementations18 Feb 2024 Felix Lambrecht, Andreas Kröpelin, Mario Lüttich, Michael Habeck, David Haselbach, Holger Stark

CowScape analyzes an entire cryo-EM dataset and thereby obtains a quantitative description of structural variability of macromolecular complexes that represents the biochemically relevant conformational space.

Density Estimation Image Classification

Parallel Affine Transformation Tuning of Markov Chain Monte Carlo

1 code implementation29 Jan 2024 Philip Schär, Michael Habeck, Daniel Rudolf

The performance of Markov chain Monte Carlo samplers strongly depends on the properties of the target distribution such as its covariance structure, the location of its probability mass and its tail behavior.

Matching biomolecular structures by registration of point clouds

no code implementations22 Jan 2024 Michael Habeck, Andreas Kröpelin, Nima Vakili

Motivation: Assessing the match between two biomolecular structures is at the heart of structural analyses such as superposition, alignment and docking.

Gibbsian polar slice sampling

1 code implementation8 Feb 2023 Philip Schär, Michael Habeck, Daniel Rudolf

Polar slice sampling (Roberts & Rosenthal, 2002) is a Markov chain approach for approximate sampling of distributions that is difficult, if not impossible, to implement efficiently, but behaves provably well with respect to the dimension.

Model evidence from nonequilibrium simulations

no code implementations NeurIPS 2017 Michael Habeck

We introduce estimators for the model evidence that combine forward and backward simulations and show for various challenging models that the evidence estimators outperform forward and reverse AIS.

Bayesian Evidence and Model Selection

no code implementations11 Nov 2014 Kevin H. Knuth, Michael Habeck, Nabin K. Malakar, Asim M. Mubeen, Ben Placek

In this paper we review the concepts of Bayesian evidence and Bayes factors, also known as log odds ratios, and their application to model selection.

Model Selection

Adaptive nonparametric detection in cryo-electron microscopy

no code implementations29 Nov 2013 Mikhail Langovoy, Michael Habeck, Bernhard Schoelkopf

Cryo-electron microscopy (cryo-EM) is an emerging experimental method to characterize the structure of large biomolecular assemblies.

Spatial statistics, image analysis and percolation theory

no code implementations31 Oct 2013 Mikhail Langovoy, Michael Habeck, Bernhard Schölkopf

We specifically address the problem of detection of multiple objects of unknown shapes in the case of nonparametric noise.

object-detection Object Detection +1

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