no code implementations • 12 Dec 2023 • Daniele Toller, Mirco Tribastone, Max Tschaikowski, Andrea Vandin
The ability to control complex networks is of crucial importance across a wide range of applications in natural and engineering sciences.
no code implementations • 20 Jan 2023 • Kim G. Larsen, Daniele Toller, Mirco Tribastone, Max Tschaikowski, Andrea Vandin
In many applications, for example, in systems biology and epidemiology, CRN parameters such as the kinetic reaction rates can be used as control inputs to steer the system toward a given target.
no code implementations • 9 Jan 2021 • Luca Cardelli, Isabel Cristina Perez-Verona, Mirco Tribastone, Max Tschaikowski, Andrea Vandin, Tabea Waizmann
Motivation: Stochastic reaction networks are a widespread model to describe biological systems where the presence of noise is relevant, such as in cell regulatory processes.
no code implementations • 12 Jun 2020 • Tabea Waizmann, Luca Bortolussi, Andrea Vandin, Mirco Tribastone
The deterministic rate equation (DRE) gives a macroscopic approximation as a compact system of differential equations that estimate the average populations for each species, but it may be inaccurate in the case of nonlinear interaction dynamics.
2 code implementations • 24 Apr 2020 • Alexey Ovchinnikov, Isabel Cristina Pérez Verona, Gleb Pogudin, Mirco Tribastone
Model reduction can help tame such complexity by providing a lower-dimensional model in which each macro-variable can be directly related to the original variables.
no code implementations • 25 Feb 2020 • Giulio Garbi, Emilio Incerto, Mirco Tribastone
It is well known that building analytical performance models in practice is difficult because it requires a considerable degree of proficiency in the underlying mathematics.