Search Results for author: Nicha C. Dvornek

Found 24 papers, 5 papers with code

SIFT-DBT: Self-supervised Initialization and Fine-Tuning for Imbalanced Digital Breast Tomosynthesis Image Classification

1 code implementation19 Mar 2024 Yuexi Du, Regina J. Hooley, John Lewin, Nicha C. Dvornek

This further exacerbates the data imbalance due to the case-level distribution in real-world data and leads to learning a trivial classification model that only predicts the majority class.

Image Classification

Learning Sequential Information in Task-based fMRI for Synthetic Data Augmentation

no code implementations29 Aug 2023 Jiyao Wang, Nicha C. Dvornek, Lawrence H. Staib, James S. Duncan

Insufficiency of training data is a persistent issue in medical image analysis, especially for task-based functional magnetic resonance images (fMRI) with spatio-temporal imaging data acquired using specific cognitive tasks.

Data Augmentation

TAI-GAN: Temporally and Anatomically Informed GAN for early-to-late frame conversion in dynamic cardiac PET motion correction

1 code implementation23 Aug 2023 Xueqi Guo, Luyao Shi, Xiongchao Chen, Bo Zhou, Qiong Liu, Huidong Xie, Yi-Hwa Liu, Richard Palyo, Edward J. Miller, Albert J. Sinusas, Bruce Spottiswoode, Chi Liu, Nicha C. Dvornek

The rapid tracer kinetics of rubidium-82 ($^{82}$Rb) and high variation of cross-frame distribution in dynamic cardiac positron emission tomography (PET) raise significant challenges for inter-frame motion correction, particularly for the early frames where conventional intensity-based image registration techniques are not applicable.

Generative Adversarial Network Image Registration +1

Copy Number Variation Informs fMRI-based Prediction of Autism Spectrum Disorder

no code implementations8 Aug 2023 Nicha C. Dvornek, Catherine Sullivan, James S. Duncan, Abha R. Gupta

We demonstrate that our attention-based model combining genetic information, demographic data, and functional magnetic resonance imaging results in superior prediction performance compared to other multimodal approaches.

severity prediction

Unsupervised inter-frame motion correction for whole-body dynamic PET using convolutional long short-term memory in a convolutional neural network

no code implementations13 Jun 2022 Xueqi Guo, Bo Zhou, David Pigg, Bruce Spottiswoode, Michael E. Casey, Chi Liu, Nicha C. Dvornek

The motion estimation network is a convolutional neural network with a combined convolutional long short-term memory layer, fully utilizing dynamic temporal features and spatial information.

Motion Estimation

Estimating Reproducible Functional Networks Associated with Task Dynamics using Unsupervised LSTMs

no code implementations6 May 2021 Nicha C. Dvornek, Pamela Ventola, James S. Duncan

We demonstrate that the functional networks learned by the LSTM model are more strongly associated with the task activity and dynamics compared to other approaches.

Time Series Time Series Analysis

Demographic-Guided Attention in Recurrent Neural Networks for Modeling Neuropathophysiological Heterogeneity

no code implementations15 Apr 2021 Nicha C. Dvornek, Xiaoxiao Li, Juntang Zhuang, Pamela Ventola, James S. Duncan

Heterogeneous presentation of a neurological disorder suggests potential differences in the underlying pathophysiological changes that occur in the brain.

Time Series Time Series Analysis

Pooling Regularized Graph Neural Network for fMRI Biomarker Analysis

no code implementations29 Jul 2020 Xiaoxiao Li, Yuan Zhou, Nicha C. Dvornek, Muhan Zhang, Juntang Zhuang, Pamela Ventola, James S. Duncan

We propose an interpretable GNN framework with a novel salient region selection mechanism to determine neurological brain biomarkers associated with disorders.

Hepatocellular Carcinoma Intra-arterial Treatment Response Prediction for Improved Therapeutic Decision-Making

no code implementations1 Dec 2019 Junlin Yang, Nicha C. Dvornek, Fan Zhang, Julius Chapiro, MingDe Lin, Aaron Abajian, James S. Duncan

This work proposes a pipeline to predict treatment response to intra-arterial therapy of patients with Hepatocellular Carcinoma (HCC) for improved therapeutic decision-making.

Decision Making

Jointly Discriminative and Generative Recurrent Neural Networks for Learning from fMRI

no code implementations15 Oct 2019 Nicha C. Dvornek, Xiaoxiao Li, Juntang Zhuang, James S. Duncan

The addition of the generative model constrains the network to learn functional communities represented by the LSTM nodes that are both consistent with the data generation as well as useful for the classification task.

Classification General Classification +2

Decision Explanation and Feature Importance for Invertible Networks

1 code implementation30 Sep 2019 Juntang Zhuang, Nicha C. Dvornek, Xiaoxiao Li, Junlin Yang, James S. Duncan

We can determine the decision boundary of a linear classifier in the feature space; since the transform is invertible, we can invert the decision boundary from the feature space to the input space.

Feature Importance

Graph Embedding Using Infomax for ASD Classification and Brain Functional Difference Detection

no code implementations9 Aug 2019 Xiaoxiao Li, Nicha C. Dvornek, Juntang Zhuang, Pamela Ventola, James Duncan

Here, we model the whole brain fMRI as a graph, which preserves geometrical and temporal information and use a Graph Neural Network (GNN) to learn from the graph-structured fMRI data.

Classification General Classification +1

Efficient Interpretation of Deep Learning Models Using Graph Structure and Cooperative Game Theory: Application to ASD Biomarker Discovery

no code implementations14 Dec 2018 Xiaoxiao Li, Nicha C. Dvornek, Yuan Zhou, Juntang Zhuang, Pamela Ventola, James S. Duncan

Cooperative game theory is advantageous here because it directly considers the interaction between features and can be applied to any machine learning method, making it a novel, more accurate way of determining instance-wise biomarker importance from deep learning models.

Feature Importance

Brain Biomarker Interpretation in ASD Using Deep Learning and fMRI

no code implementations23 Aug 2018 Xiaoxiao Li, Nicha C. Dvornek, Juntang Zhuang, Pamela Ventola, James S. Duncan

Therefore, in this work, we address the problem of interpreting reliable biomarkers associated with identifying ASD; specifically, we propose a 2-stage method that classifies ASD and control subjects using fMRI images and interprets the saliency features activated by the classifier.

Decision Making

Prediction of Autism Treatment Response from Baseline fMRI using Random Forests and Tree Bagging

no code implementations24 May 2018 Nicha C. Dvornek, Daniel Yang, Archana Venkataraman, Pamela Ventola, Lawrence H. Staib, Kevin A. Pelphrey, James S. Duncan

We propose predicting patient response to PRT from baseline task-based fMRI by the novel application of a random forest and tree bagging strategy.

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