Search Results for author: Nicholas J. Seewald

Found 1 papers, 1 papers with code

Sample size considerations for comparing dynamic treatment regimens in a sequential multiple-assignment randomized trial with a continuous longitudinal outcome

1 code implementation31 Oct 2018 Nicholas J. Seewald, Kelley M. Kidwell, Inbal Nahum-Shani, Tianshuang Wu, James R. McKay, Daniel Almirall

We show that the sample size formula for a SMART can be written as the product of the sample size formula for a standard two-arm randomized trial, a deflation factor that accounts for the increased statistical efficiency resulting from a repeated-measures analysis, and an inflation factor that accounts for the design of a SMART.

Methodology

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