Transformer-based Model for Oral Epithelial Dysplasia Segmentation

no code implementations • 9 Nov 2023 • Adam J Shephard, Hanya Mahmood, Shan E Ahmed Raza, Anna Luiza Damaceno Araujo, Alan Roger Santos-Silva, Marcio Ajudarte Lopes, Pablo Agustin Vargas, Kris McCombe, Stephanie Craig, Jacqueline James, Jill Brooks, Paul Nankivell, Hisham Mehanna, Syed Ali Khurram, Nasir M Rajpoot

Oral epithelial dysplasia (OED) is a premalignant histopathological diagnosis given to lesions of the oral cavity.

Segmentation whole slide images

A Fully Automated and Explainable Algorithm for the Prediction of Malignant Transformation in Oral Epithelial Dysplasia

no code implementations • 6 Jul 2023 • Adam J Shephard, Raja Muhammad Saad Bashir, Hanya Mahmood, Mostafa Jahanifar, Fayyaz Minhas, Shan E Ahmed Raza, Kris D McCombe, Stephanie G Craig, Jacqueline James, Jill Brooks, Paul Nankivell, Hisham Mehanna, Syed Ali Khurram, Nasir M Rajpoot

To address this, we developed a novel artificial intelligence algorithm that can assign an Oral Malignant Transformation (OMT) risk score, based on histological patterns in the in Haematoxylin and Eosin stained whole slide images, to quantify the risk of OED progression.

whole slide images

A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma

no code implementations • 16 Apr 2021 • Muhammad Shaban, Shan E Ahmed Raza, Mariam Hassan, Arif Jamshed, Sajid Mushtaq, Asif Loya, Nikolaos Batis, Jill Brooks, Paul Nankivell, Neil Sharma, Max Robinson, Hisham Mehanna, Syed Ali Khurram, Nasir Rajpoot

In this study, our aim is to explore the prognostic significance of tumour-associated stroma infiltrating lymphocytes (TASILs) in head and neck squamous cell carcinoma (HNSCC) through an AI based automated method.

Clinical Knowledge whole slide images