Search Results for author: Peter F. Stadler

Found 14 papers, 1 papers with code

On the Realisability of Chemical Pathways

no code implementations19 Sep 2023 Jakob L. Andersen, Sissel Banke, Rolf Fagerberg, Christoph Flamm, Daniel Merkle, Peter F. Stadler

The exploration of pathways and alternative pathways that have a specific function is of interest in numerous chemical contexts.

Unstable Cores are the source of instability in chemical reaction networks

no code implementations22 Aug 2023 Nicola Vassena, Peter F. Stadler

In biochemical networks, complex dynamical features such as superlinear growth and oscillations are classically considered a consequence of autocatalysis.

The Theory of Gene Family Histories

no code implementations24 Apr 2023 Marc Hellmuth, Peter F. Stadler

Most genes are part of larger families of evolutionary related genes.

Optimisation via encodings: a renormalisation group perspective

no code implementations28 Mar 2023 Konstantin Klemm, Anita Mehta, Peter F. Stadler

Difficult, in particular NP-complete, optimization problems are traditionally solved approximately using search heuristics.

Relative Timing Information and Orthology in Evolutionary Scenarios

no code implementations5 Dec 2022 David Schaller, Tom Hartmann, Manuel Lafond, Nicolas Wieseke, Peter F. Stadler, Marc Hellmuth

The relative timing information of gene and species divergences is captured by three colored graphs that have the extant genes as vertices and the species in which the genes are found as vertex colors: the equal-divergence-time (EDT) graph, the later-divergence-time (LDT) graph and the prior-divergence-time (PDT) graph, which together form an edge partition of the complete graph.

Clustering Systems of Phylogenetic Networks

no code implementations28 Apr 2022 Marc Hellmuth, David Schaller, Peter F. Stadler

The main results are correspondences of classes of networks and clustering system of the following form: If $N$ is a network of type $\mathbb{X}$, then $\mathcal{C}_N$ satisfies $\mathbb{Y}$, and conversely if $\mathscr{C}$ is a clustering system satisfying $\mathbb{Y}$ then there is network $N$ of type $\mathbb{X}$ such that $\mathscr{C}\subseteq\mathscr{C}_N$. This, in turn, allows us to investigate the mutual dependencies between the distinct types of networks in much detail.

Clustering

What makes a reaction network "chemical"?

no code implementations5 Jan 2022 Stefan Müller, Christoph Flamm, Peter F. Stadler

In particular, these realizations can be chosen such that any two species have distinct sum formulas, unless $\mathbf{S}$ implies that they are "obligatory isomers".

Defining Autocatalysis in Chemical Reaction Networks

no code implementations7 Jul 2021 Jakob L. Andersen, Christoph Flamm, Daniel Merkle, Peter F. Stadler

Given a chemical reaction network, however, it is not at all straightforward to identify species that are autocatalytic in the sense that there is a sub-network that takes $X$ as input and produces more than one copy of $X$ as output.

Arc-Completion of 2-Colored Best Match Graphs to Binary-Explainable Best Match Graphs

no code implementations11 Mar 2021 David Schaller, Manuela Geiß, Marc Hellmuth, Peter F. Stadler

For the special case of two-colored BMGs, this leads to a characterization of the least resolved trees (LRTs) of binary-explainable trees and a simple, polynomial-time algorithm for the minimum cardinality completion of the arc set of a BMG to reach a BMG that can be explained by a binary tree.

Data Structures and Algorithms Discrete Mathematics Combinatorics Populations and Evolution

From Modular Decomposition Trees to Rooted Median Graphs

no code implementations11 Mar 2021 Carmen Bruckmann, Peter F. Stadler, Marc Hellmuth

The modular decomposition of a symmetric map $\delta\colon X\times X \to \Upsilon$ (or, equivalently, a set of symmetric binary relations, a 2-structure, or an edge-colored undirected graph) is a natural construction to capture key features of $\delta$ in labeled trees.

Combinatorics Discrete Mathematics

Least resolved trees for two-colored best match graphs

no code implementations18 Jan 2021 David Schaller, Manuela Geiß, Marc Hellmuth, Peter F. Stadler

Introducing the concept of support vertices we derive an $O(|V|+|E|\log^2|V|)$-time algorithm to recognize 2-BMGs and to construct its LRT.

Vocal Bursts Valence Prediction

Indirect Identification of Horizontal Gene Transfer

no code implementations16 Dec 2020 David Schaller, Manuel Lafond, Peter F. Stadler, Nicolas Wieseke, Marc Hellmuth

An edge in an LDT graph implies that the two corresponding genes are separated by at least one HGT event.

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