Search Results for author: Philip R. O. Payne

Found 6 papers, 1 papers with code

Highly Accurate Disease Diagnosis and Highly Reproducible Biomarker Identification with PathFormer

no code implementations11 Feb 2024 Zehao Dong, Qihang Zhao, Philip R. O. Payne, Michael A Province, Carlos Cruchaga, Muhan Zhang, Tianyu Zhao, Yixin Chen, Fuhai Li

However, we found two major limitations of existing GNNs in omics data analysis, i. e., limited-prediction (diagnosis) accuracy and limited-reproducible biomarker identification capacity across multiple datasets.

Self-explaining Neural Network with Concept-based Explanations for ICU Mortality Prediction

no code implementations9 Oct 2021 Sayantan Kumar, Sean C. Yu, Thomas Kannampallil, Zachary Abrams, Andrew Michelson, Philip R. O. Payne

Complex deep learning models show high prediction tasks in various clinical prediction tasks but their inherent complexity makes it more challenging to explain model predictions for clinicians and healthcare providers.

Explainable Models ICU Mortality

Repurposing drugs for COVID-19 based on transcriptional response of host cells to SARS-CoV-2

1 code implementation1 Jun 2020 Fuhai Li, Andrew P. Michelson, Randi Foraker, Ming Zhan, Philip R. O. Payne

Based on the identified signaling pathways and GOs, a set of potentially effective drugs were repurposed by integrating the drug-target and reverse gene expression data resources.

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