no code implementations • 29 May 2023 • Philippe Weitz, Masi Valkonen, Leslie Solorzano, Circe Carr, Kimmo Kartasalo, Constance Boissin, Sonja Koivukoski, Aino Kuusela, Dusan Rasic, Yanbo Feng, Sandra Sinius Pouplier, Abhinav Sharma, Kajsa Ledesma Eriksson, Stephanie Robertson, Christian Marzahl, Chandler D. Gatenbee, Alexander R. A. Anderson, Marek Wodzinski, Artur Jurgas, Niccolò Marini, Manfredo Atzori, Henning Müller, Daniel Budelmann, Nick Weiss, Stefan Heldmann, Johannes Lotz, Jelmer M. Wolterink, Bruno De Santi, Abhijeet Patil, Amit Sethi, Satoshi Kondo, Satoshi Kasai, Kousuke Hirasawa, Mahtab Farrokh, Neeraj Kumar, Russell Greiner, Leena Latonen, Anne-Vibeke Laenkholm, Johan Hartman, Pekka Ruusuvuori, Mattias Rantalainen
The alignment of tissue between histopathological whole-slide-images (WSI) is crucial for research and clinical applications.
no code implementations • 12 Mar 2023 • Philippe Weitz, Viktoria Sartor, Balazs Acs, Stephanie Robertson, Daniel Budelmann, Johan Hartman, Mattias Rantalainen
This indicates that WSI registration has the potential to reduce the need for IHC-specific annotations.
no code implementations • 24 Nov 2022 • Philippe Weitz, Masi Valkonen, Leslie Solorzano, Circe Carr, Kimmo Kartasalo, Constance Boissin, Sonja Koivukoski, Aino Kuusela, Dusan Rasic, Yanbo Feng, Sandra Kristiane Sinius Pouplier, Abhinav Sharma, Kajsa Ledesma Eriksson, Leena Latonen, Anne-Vibeke Laenkholm, Johan Hartman, Pekka Ruusuvuori, Mattias Rantalainen
In particular, there are no large, high quality publicly available data sets with WSIs of matching IHC and H&E-stained tissue sections.
no code implementations • 27 Jun 2021 • Bojing Liu, Yinxi Wang, Philippe Weitz, Johan Lindberg, Johan Hartman, Lars Egevad, Henrik Grönberg, Martin Eklund, Mattias Rantalainen
As a proof-of-principle, we developed and validated a deep convolutional neural network model to distinguish between morphological patterns in benign prostate biopsy whole slide images from men with and without established cancer.
1 code implementation • 19 Apr 2021 • Philippe Weitz, Yinxi Wang, Kimmo Kartasalo, Lars Egevad, Johan Lindberg, Henrik Grönberg, Martin Eklund, Mattias Rantalainen
Molecular phenotyping by gene expression profiling is common in contemporary cancer research and in molecular diagnostics.
no code implementations • 13 Oct 2019 • Christoph Haarburger, Justus Schock, Daniel Truhn, Philippe Weitz, Gustav Mueller-Franzes, Leon Weninger, Dorit Merhof
From these segmentations, we extract a high number of plausible feature vectors for each lung tumor and analyze feature variance with respect to the segmentations.
no code implementations • 29 Aug 2018 • Christoph Haarburger, Philippe Weitz, Oliver Rippel, Dorit Merhof
Traditional survival models such as the Cox proportional hazards model are typically based on scalar or categorical clinical features.