no code implementations • 10 May 2023 • Wang-Yu Tong, Yong Li, Shou-Dong Ye, An-Jing Wang, Yan-Yan Tang, Mei-Li Li, Zhong-Fan Yu, Ting-Ting Xia, Qing-Yang Liu, Si-Qi Zhu
RNA-guided gene editing based on the CRISPR-Cas system is currently the most effective genome editing technique.
no code implementations • 8 May 2023 • Wang-Yu Tong, De-Xiang Yong, Xin Xu, Cai-Hua Qiu, Yan Zhang, Xing-Wang Yang, Ting-Ting Xia, Qing-Yang Liu, Su-Li Cao, Yan Sun, Xue Li
Type I CRISPR-Cas systems are the most common among six types of CRISPR-Cas systems, however, non-self-targeting genome editing based on a single Cas3 of type I CRISPR-Cas systems has not been reported.