Search Results for author: Robert Dürichen

Found 7 papers, 0 papers with code

Enabling scalable clinical interpretation of ML-based phenotypes using real world data

no code implementations2 Aug 2022 Owen Parsons, Nathan E Barlow, Janie Baxter, Karen Paraschin, Andrea Derix, Peter Hein, Robert Dürichen

This endangers the final step of analysis where an actionable and clinically meaningful interpretation is needed. This study investigates approaches to perform patient stratification analysis at scale using large EHR datasets and multiple clustering methods for clinical research.

Clustering

Similarity-based prediction of Ejection Fraction in Heart Failure Patients

no code implementations14 Mar 2022 Jamie Wallis, Andres Azqueta-Gavaldon, Thanusha Ananthakumar, Robert Dürichen, Luca Albergante

Biomedical research is increasingly employing real world evidence (RWE) to foster discoveries of novel clinical phenotypes and to better characterize long term effect of medical treatments.

Imputation

Compensating trajectory bias for unsupervised patient stratification using adversarial recurrent neural networks

no code implementations14 Dec 2021 Avelino Javer, Owen Parsons, Oliver Carr, Janie Baxter, Christian Diedrich, Eren Elçi, Steffen Schaper, Katrin Coboeken, Robert Dürichen

Electronic healthcare records are an important source of information which can be used in patient stratification to discover novel disease phenotypes.

Longitudinal patient stratification of electronic health records with flexible adjustment for clinical outcomes

no code implementations11 Nov 2021 Oliver Carr, Avelino Javer, Patrick Rockenschaub, Owen Parsons, Robert Dürichen

We demonstrate the model performance on $29, 229$ diabetes patients, showing it finds clusters of patients with both different trajectories and different outcomes which can be utilized to aid clinical decision making.

Clustering Decision Making

Deep Semi-Supervised Embedded Clustering (DSEC) for Stratification of Heart Failure Patients

no code implementations24 Dec 2020 Oliver Carr, Stojan Jovanovic, Luca Albergante, Fernando Andreotti, Robert Dürichen, Nadia Lipunova, Janie Baxter, Rabia Khan, Benjamin Irving

In this work we apply deep semi-supervised embedded clustering to determine data-driven patient subgroups of heart failure from the electronic health records of 4, 487 heart failure and control patients.

Clustering

Binary Input Layer: Training of CNN models with binary input data

no code implementations9 Dec 2018 Robert Dürichen, Thomas Rocznik, Oliver Renz, Christian Peters

For the efficient execution of deep convolutional neural networks (CNN) on edge devices, various approaches have been presented which reduce the bit width of the network parameters down to 1 bit.

Binarization

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