no code implementations • 2 Aug 2022 • Owen Parsons, Nathan E Barlow, Janie Baxter, Karen Paraschin, Andrea Derix, Peter Hein, Robert Dürichen
This endangers the final step of analysis where an actionable and clinically meaningful interpretation is needed. This study investigates approaches to perform patient stratification analysis at scale using large EHR datasets and multiple clustering methods for clinical research.
no code implementations • 14 Mar 2022 • Jamie Wallis, Andres Azqueta-Gavaldon, Thanusha Ananthakumar, Robert Dürichen, Luca Albergante
Biomedical research is increasingly employing real world evidence (RWE) to foster discoveries of novel clinical phenotypes and to better characterize long term effect of medical treatments.
no code implementations • 14 Dec 2021 • Avelino Javer, Owen Parsons, Oliver Carr, Janie Baxter, Christian Diedrich, Eren Elçi, Steffen Schaper, Katrin Coboeken, Robert Dürichen
Electronic healthcare records are an important source of information which can be used in patient stratification to discover novel disease phenotypes.
no code implementations • 11 Nov 2021 • Oliver Carr, Avelino Javer, Patrick Rockenschaub, Owen Parsons, Robert Dürichen
We demonstrate the model performance on $29, 229$ diabetes patients, showing it finds clusters of patients with both different trajectories and different outcomes which can be utilized to aid clinical decision making.
no code implementations • 24 Dec 2020 • Oliver Carr, Stojan Jovanovic, Luca Albergante, Fernando Andreotti, Robert Dürichen, Nadia Lipunova, Janie Baxter, Rabia Khan, Benjamin Irving
In this work we apply deep semi-supervised embedded clustering to determine data-driven patient subgroups of heart failure from the electronic health records of 4, 487 heart failure and control patients.
no code implementations • 16 Jul 2020 • Fernando Andreotti, Frank S. Heldt, Basel Abu-Jamous, Ming Li, Avelino Javer, Oliver Carr, Stojan Jovanovic, Nadezda Lipunova, Benjamin Irving, Rabia T. Khan, Robert Dürichen
The proposed approach is compared to a standard clinical risk predictor (QRISK) and machine learning alternatives using 5-year data from a NHS Foundation Trust.
no code implementations • 9 Dec 2018 • Robert Dürichen, Thomas Rocznik, Oliver Renz, Christian Peters
For the efficient execution of deep convolutional neural networks (CNN) on edge devices, various approaches have been presented which reduce the bit width of the network parameters down to 1 bit.