Search Results for author: Sebastian Pölsterl

Found 20 papers, 11 papers with code

Keep the Faith: Faithful Explanations in Convolutional Neural Networks for Case-Based Reasoning

1 code implementation15 Dec 2023 Tom Nuno Wolf, Fabian Bongratz, Anne-Marie Rickmann, Sebastian Pölsterl, Christian Wachinger

During inference, similarities of latent features to prototypes are linearly classified to form predictions and attribution maps are provided to explain the similarity.

Don't PANIC: Prototypical Additive Neural Network for Interpretable Classification of Alzheimer's Disease

1 code implementation13 Mar 2023 Tom Nuno Wolf, Sebastian Pölsterl, Christian Wachinger

We propose PANIC, a prototypical additive neural network for interpretable AD classification that integrates 3D image and tabular data.

Joint Reconstruction and Parcellation of Cortical Surfaces

no code implementations19 Sep 2022 Anne-Marie Rickmann, Fabian Bongratz, Sebastian Pölsterl, Ignacio Sarasua, Christian Wachinger

The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD).

3D Reconstruction Graph Classification +1

CASHformer: Cognition Aware SHape Transformer for Longitudinal Analysis

no code implementations5 Jul 2022 Ignacio Sarasua, Sebastian Pölsterl, Christian Wachinger

To this end, we introduce CASHformer, a transformer-based framework to model longitudinal shape trajectories in AD.

Hippocampus

Is a PET all you need? A multi-modal study for Alzheimer's disease using 3D CNNs

no code implementations5 Jul 2022 Marla Narazani, Ignacio Sarasua, Sebastian Pölsterl, Aldana Lizarraga, Igor Yakushev, Christian Wachinger

AD classification and focus on differential diagnosis of dementia, where fusing multi-modal image information conforms with a clinical need.

Clinical Knowledge

Vox2Cortex: Fast Explicit Reconstruction of Cortical Surfaces from 3D MRI Scans with Geometric Deep Neural Networks

1 code implementation CVPR 2022 Fabian Bongratz, Anne-Marie Rickmann, Sebastian Pölsterl, Christian Wachinger

The reconstruction of cortical surfaces from brain magnetic resonance imaging (MRI) scans is essential for quantitative analyses of cortical thickness and sulcal morphology.

Alzheimer's Disease Diagnosis via Deep Factorization Machine Models

no code implementations12 Aug 2021 Raphael Ronge, Kwangsik Nho, Christian Wachinger, Sebastian Pölsterl

The current state-of-the-art deep neural networks (DNNs) for Alzheimer's Disease diagnosis use different biomarker combinations to classify patients, but do not allow extracting knowledge about the interactions of biomarkers.

Scalable, Axiomatic Explanations of Deep Alzheimer's Diagnosis from Heterogeneous Data

1 code implementation13 Jul 2021 Sebastian Pölsterl, Christina Aigner, Christian Wachinger

We propose Shapley Value Explanation of Heterogeneous Neural Networks (SVEHNN) for explaining the Alzheimer's diagnosis made by a DNN from the 3D point cloud of the neuroanatomy and tabular biomarkers.

Decision Making

Combining 3D Image and Tabular Data via the Dynamic Affine Feature Map Transform

2 code implementations13 Jul 2021 Sebastian Pölsterl, Tom Nuno Wolf, Christian Wachinger

Prior work on diagnosing Alzheimer's disease from magnetic resonance images of the brain established that convolutional neural networks (CNNs) can leverage the high-dimensional image information for classifying patients.

Semi-Structured Deep Piecewise Exponential Models

no code implementations11 Nov 2020 Philipp Kopper, Sebastian Pölsterl, Christian Wachinger, Bernd Bischl, Andreas Bender, David Rügamer

We propose a versatile framework for survival analysis that combines advanced concepts from statistics with deep learning.

Survival Analysis

Estimation of Causal Effects in the Presence of Unobserved Confounding in the Alzheimer's Continuum

1 code implementation23 Jun 2020 Sebastian Pölsterl, Christian Wachinger

We derive a causal graph from the current clinical knowledge on cause and effect in the Alzheimer's disease continuum, and show that identifiability of the causal effect requires all confounders to be known and measured.

Causal Inference Clinical Knowledge

Detect and Correct Bias in Multi-Site Neuroimaging Datasets

1 code implementation12 Feb 2020 Christian Wachinger, Anna Rieckmann, Sebastian Pölsterl

Given such evidence, we take a closer look at confounding bias, which is often viewed as the main shortcoming in observational studies.

Quantifying Confounding Bias in Neuroimaging Datasets with Causal Inference

no code implementations9 Jul 2019 Christian Wachinger, Benjamin Gutierrez Becker, Anna Rieckmann, Sebastian Pölsterl

In this work, we combine 12, 207 MRI scans from 15 studies and show that simple pooling is often ill-advised due to introducing various types of biases in the training data.

Causal Inference

Adversarial Learned Molecular Graph Inference and Generation

1 code implementation24 May 2019 Sebastian Pölsterl, Christian Wachinger

Recent methods for generating novel molecules use graph representations of molecules and employ various forms of graph convolutional neural networks for inference.

Drug Discovery

BrainTorrent: A Peer-to-Peer Environment for Decentralized Federated Learning

no code implementations16 May 2019 Abhijit Guha Roy, Shayan Siddiqui, Sebastian Pölsterl, Nassir Navab, Christian Wachinger

A disadvantage of FL is the dependence on a central server, which requires all clients to agree on one trusted central body, and whose failure would disrupt the training process of all clients.

Brain Segmentation Federated Learning

An Efficient Training Algorithm for Kernel Survival Support Vector Machines

2 code implementations21 Nov 2016 Sebastian Pölsterl, Nassir Navab, Amin Katouzian

Survival analysis is a fundamental tool in medical research to identify predictors of adverse events and develop systems for clinical decision support.

Survival Analysis

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