1 code implementation • 4 Apr 2021 • Seyednami Niyakan, Ehsan Hajiramezanali, Shahin Boluki, Siamak Zamani Dadaneh, Xiaoning Qian
We develop a new method -- SimCD -- that explicitly models cell heterogeneity and dynamic differential changes in one unified hierarchical gamma-negative binomial (hGNB) model, allowing simultaneous cell clustering and differential expression analysis for scRNA-seq data.
no code implementations • 21 May 2020 • Siamak Zamani Dadaneh, Shahin Boluki, Mingzhang Yin, Mingyuan Zhou, Xiaoning Qian
Semantic hashing has become a crucial component of fast similarity search in many large-scale information retrieval systems, in particular, for text data.
no code implementations • 12 Feb 2020 • Shahin Boluki, Randy Ardywibowo, Siamak Zamani Dadaneh, Mingyuan Zhou, Xiaoning Qian
In this work, we propose learnable Bernoulli dropout (LBD), a new model-agnostic dropout scheme that considers the dropout rates as parameters jointly optimized with other model parameters.
no code implementations • 1 Nov 2019 • Siamak Zamani Dadaneh, Shahin Boluki, Mingyuan Zhou, Xiaoning Qian
Learning-to-rank methods can generally be categorized into pointwise, pairwise, and listwise approaches.
no code implementations • 26 Feb 2019 • Shahin Boluki, Siamak Zamani Dadaneh, Xiaoning Qian, Edward R. Dougherty
Missing values frequently arise in modern biomedical studies due to various reasons, including missing tests or complex profiling technologies for different omics measurements.
no code implementations • NeurIPS 2018 • Ehsan Hajiramezanali, Siamak Zamani Dadaneh, Alireza Karbalayghareh, Mingyuan Zhou, Xiaoning Qian
Second, compared to the number of involved molecules and system complexity, the number of available samples for studying complex disease, such as cancer, is often limited, especially considering disease heterogeneity.
no code implementations • 7 Mar 2018 • Ehsan Hajiramezanali, Siamak Zamani Dadaneh, Paul de Figueiredo, Sing-Hoi Sze, Mingyuan Zhou, Xiaoning Qian
Next-generation sequencing (NGS) to profile temporal changes in living systems is gaining more attention for deriving better insights into the underlying biological mechanisms compared to traditional static sequencing experiments.