1 code implementation • 11 Apr 2023 • Omar S. M. El Nahhas, Chiara M. L. Loeffler, Zunamys I. Carrero, Marko van Treeck, Fiona R. Kolbinger, Katherine J. Hewitt, Hannah S. Muti, Mara Graziani, Qinghe Zeng, Julien Calderaro, Nadina Ortiz-Brüchle, Tanwei Yuan, Michael Hoffmeister, Hermann Brenner, Alexander Brobeil, Jorge S. Reis-Filho, Jakob Nikolas Kather
We tested our method for multiple clinically and biologically relevant biomarkers: homologous repair deficiency (HRD) score, a clinically used pan-cancer biomarker, as well as markers of key biological processes in the tumor microenvironment.
2 code implementations • 23 Jan 2023 • Sophia J. Wagner, Daniel Reisenbüchler, Nicholas P. West, Jan Moritz Niehues, Gregory Patrick Veldhuizen, Philip Quirke, Heike I. Grabsch, Piet A. van den Brandt, Gordon G. A. Hutchins, Susan D. Richman, Tanwei Yuan, Rupert Langer, Josien Christina Anna Jenniskens, Kelly Offermans, Wolfram Mueller, Richard Gray, Stephen B. Gruber, Joel K. Greenson, Gad Rennert, Joseph D. Bonner, Daniel Schmolze, Jacqueline A. James, Maurice B. Loughrey, Manuel Salto-Tellez, Hermann Brenner, Michael Hoffmeister, Daniel Truhn, Julia A. Schnabel, Melanie Boxberg, Tingying Peng, Jakob Nikolas Kather
Methods: In this study, we developed a new fully transformer-based pipeline for end-to-end biomarker prediction from pathology slides.