no code implementations • 8 Feb 2024 • Thomas A. Lasko, John M. Still, Thomas Z. Li, Marco Barbero Mota, William W. Stead, Eric V. Strobl, Bennett A. Landman, Fabien Maldonado
Insufficiently precise diagnosis of clinical disease is likely responsible for many treatment failures, even for common conditions and treatments.
no code implementations • 8 Nov 2023 • Thomas A. Lasko, Eric V. Strobl, William W. Stead
The rising popularity of artificial intelligence in healthcare is highlighting the problem that a computational model achieving super-human clinical performance at its training sites may perform substantially worse at new sites.
1 code implementation • 6 Apr 2023 • Thomas Z. Li, John M. Still, Kaiwen Xu, Ho Hin Lee, Leon Y. Cai, Aravind R. Krishnan, Riqiang Gao, Mirza S. Khan, Sanja Antic, Michael Kammer, Kim L. Sandler, Fabien Maldonado, Bennett A. Landman, Thomas A. Lasko
In this work, we propose a transformer-based multimodal strategy to integrate repeat imaging with longitudinal clinical signatures from routinely collected EHRs for SPN classification.
no code implementations • 27 Oct 2022 • Eric V. Strobl, Thomas A. Lasko
Root causal analysis seeks to identify the set of initial perturbations that induce an unwanted outcome.
1 code implementation • 28 Sep 2022 • Xin Yu, Qi Yang, Yinchi Zhou, Leon Y. Cai, Riqiang Gao, Ho Hin Lee, Thomas Li, Shunxing Bao, Zhoubing Xu, Thomas A. Lasko, Richard G. Abramson, Zizhao Zhang, Yuankai Huo, Bennett A. Landman, Yucheng Tang
Transformer-based models, capable of learning better global dependencies, have recently demonstrated exceptional representation learning capabilities in computer vision and medical image analysis.
1 code implementation • 4 Sep 2022 • Thomas Z. Li, Kaiwen Xu, Riqiang Gao, Yucheng Tang, Thomas A. Lasko, Fabien Maldonado, Kim Sandler, Bennett A. Landman
In cross-validation on screening chest CTs from the NLST, our methods (0. 785 and 0. 786 AUC respectively) significantly outperform a cross-sectional approach (0. 734 AUC) and match the discriminative performance of the leading longitudinal medical imaging algorithm (0. 779 AUC) on benign versus malignant classification.
no code implementations • 17 Jun 2022 • Riqiang Gao, Thomas Li, Yucheng Tang, Zhoubing Xu, Michael Kammer, Sanja L. Antic, Kim Sandler, Fabien Moldonado, Thomas A. Lasko, Bennett Landman
We believe that this study has merits to guide readers to choose calibration models and understand gaps between general computer vision and medical imaging domains.
no code implementations • 25 May 2022 • Eric V. Strobl, Thomas A. Lasko
Complex diseases are caused by a multitude of factors that may differ between patients even within the same diagnostic category.
1 code implementation • 23 May 2022 • Eric V. Strobl, Thomas A. Lasko
Complex diseases are caused by a multitude of factors that may differ between patients.
no code implementations • 4 Mar 2022 • Xin Yu, Yucheng Tang, Yinchi Zhou, Riqiang Gao, Qi Yang, Ho Hin Lee, Thomas Li, Shunxing Bao, Yuankai Huo, Zhoubing Xu, Thomas A. Lasko, Richard G. Abramson, Bennett A. Landman
Efficiently quantifying renal structures can provide distinct spatial context and facilitate biomarker discovery for kidney morphology.
1 code implementation • 25 Nov 2021 • Eric V. Strobl, Thomas A. Lasko
This assumption allows us to extrapolate results from exclusive trials to the broader population by analyzing observational and trial data simultaneously using an algorithm called Optimum in Convex Hulls (OCH).
no code implementations • 25 Jul 2021 • Riqiang Gao, Yucheng Tang, Kaiwen Xu, Ho Hin Lee, Steve Deppen, Kim Sandler, Pierre Massion, Thomas A. Lasko, Yuankai Huo, Bennett A. Landman
To our knowledge, it is the first generative adversarial model that addresses multi-modal missing imputation by modeling the joint distribution of image and non-image data.
no code implementations • 2 May 2021 • Eric V. Strobl, Thomas A. Lasko
We instead propose Synthesized Difference in Differences (SDD) that infers the correct (possibly non-parallel) slopes by linearly adjusting a conditional version of DD using additional RCT data.
no code implementations • 17 Mar 2020 • Colin B. Hansen, Vishwesh Nath, Diego A. Mesa, Yuankai Huo, Bennett A. Landman, Thomas A. Lasko
But in some learning problems, partial label information can be inferred from otherwise unlabeled examples and used to further improve the model.
1 code implementation • 23 Jun 2019 • Yuankai Huo, James G. Terry, Jiachen Wang, Sangeeta Nair, Thomas A. Lasko, Barry I. Freedman, J. Jeffery Carr, Bennett A. Landman
Manually tracing regions of interest (ROIs) within the liver is the de facto standard method for measuring liver attenuation on computed tomography (CT) in diagnosing nonalcoholic fatty liver disease (NAFLD).
no code implementations • 19 Feb 2014 • Thomas A. Lasko
Finally, we apply the method to clinical event data and demonstrate the face-validity of the abstraction, which is now amenable to standard learning algorithms.