no code implementations • 12 Feb 2024 • Douwe J. Spaanderman, Martijn P. A. Starmans, Gonnie C. M. van Erp, David F. Hanff, Judith H. Sluijter, Anne-Rose W. Schut, Geert J. L. H. van Leenders, Cornelis Verhoef, Dirk J. Grunhagen, Wiro J. Niessen, Jacob J. Visser, Stefan Klein
Next, the method was externally validated on a dataset including five unseen STT phenotypes in extremities, achieving 0. 81$\pm$0. 08 for CT, 0. 84$\pm$0. 09 for T1-weighted MRI, and 0. 88\pm0. 08 for previously unseen T2-weighted fat-saturated (FS) MRI.
1 code implementation • 13 Jan 2024 • Sijie Liu, Ruisheng Su, Jianghang Su, Jingmin Xin, Jiayi Wu, Wim van Zwam, Pieter Jan van Doormaal, Aad van der Lugt, Wiro J. Niessen, Nanning Zheng, Theo van Walsum
In this paper, we consider automatic lumen segmentation generation without additional annotation effort by physicians and more effective use of the generated lumen segmentation for improved centerline extraction performance.
no code implementations • 29 Jun 2022 • Vikram Venkatraghavan, Sebastian R. van der Voort, Daniel Bos, Marion Smits, Frederik Barkhof, Wiro J. Niessen, Stefan Klein, Esther E. Bron
Regarding prediction, i. e. estimation of the future 'condition' of the patient, we will zoom in on use cases such as predicting the disease course in multiple sclerosis and predicting patient outcomes after treatment in brain cancer.
1 code implementation • Nature Communications Biology 2021 • Arno van Hilten, Seven A. Kushner, Manfred Kayser, M. Arfan Ikram, Hieab H. H. Adams, Caroline C. W. Klaver, Wiro J. Niessen, Gennady V. Roshchupkin
Here, we propose GenNet, a novel open-source deep learning framework for predicting phenotypes from genetic variants.
2 code implementations • 19 Aug 2021 • Martijn P. A. Starmans, Sebastian R. van der Voort, Thomas Phil, Milea J. M. Timbergen, Melissa Vos, Guillaume A. Padmos, Wouter Kessels, David Hanff, Dirk J. Grunhagen, Cornelis Verhoef, Stefan Sleijfer, Martin J. van den Bent, Marion Smits, Roy S. Dwarkasing, Christopher J. Els, Federico Fiduzi, Geert J. L. H. van Leenders, Anela Blazevic, Johannes Hofland, Tessa Brabander, Renza A. H. van Gils, Gaston J. H. Franssen, Richard A. Feelders, Wouter W. de Herder, Florian E. Buisman, Francois E. J. A. Willemssen, Bas Groot Koerkamp, Lindsay Angus, Astrid A. M. van der Veldt, Ana Rajicic, Arlette E. Odink, Mitchell Deen, Jose M. Castillo T., Jifke Veenland, Ivo Schoots, Michel Renckens, Michail Doukas, Rob A. de Man, Jan N. M. IJzermans, Razvan L. Miclea, Peter B. Vermeulen, Esther E. Bron, Maarten G. Thomeer, Jacob J. Visser, Wiro J. Niessen, Stefan Klein
In this study we propose a framework for automatically optimizing the construction of radiomics workflows per application.
1 code implementation • 28 Dec 2020 • Bo Li, Wiro J. Niessen, Stefan Klein, Marius de Groot, M. Arfan Ikram, Meike W. Vernooij, Esther E. Bron
This work presents a single-step deep-learning framework for longitudinal image analysis, coined Segis-Net.
no code implementations • 16 Dec 2020 • Esther E. Bron, Stefan Klein, Janne M. Papma, Lize C. Jiskoot, Vikram Venkatraghavan, Jara Linders, Pauline Aalten, Peter Paul De Deyn, Geert Jan Biessels, Jurgen A. H. R. Claassen, Huub A. M. Middelkoop, Marion Smits, Wiro J. Niessen, John C. van Swieten, Wiesje M. van der Flier, Inez H. G. B. Ramakers, Aad van der Lugt
For prediction in MCI, performances decreased for both SVM (0. 665) and CNN (0. 702).
no code implementations • 3 Nov 2020 • Bo Li, Wiro J. Niessen, Stefan Klein, M. Arfan Ikram, Meike W. Vernooij, Esther E. Bron
We here propose an analytical framework based on an unbiased learning strategy for group-wise registration that simultaneously registers images to the mean space of a group to obtain consistent segmentations.
1 code implementation • 14 Oct 2020 • Martijn P. A. Starmans, Milea J. M. Timbergen, Melissa Vos, Michel Renckens, Dirk J. Grünhagen, Geert J. L. H. van Leenders, Roy S. Dwarkasing, François E. J. A. Willemssen, Wiro J. Niessen, Cornelis Verhoef, Stefan Sleijfer, Jacob J. Visser, Stefan Klein
The aim of this study was to evaluate radiomics for distinguishing GISTs from other intra-abdominal tumors, and in GISTs, predict the c-KIT, PDGFRA, BRAF mutational status and mitotic index (MI).
no code implementations • 9 Oct 2020 • Sebastian R. van der Voort, Fatih Incekara, Maarten M. J. Wijnenga, Georgios Kapsas, Renske Gahrmann, Joost W. Schouten, Rishi Nandoe Tewarie, Geert J. Lycklama, Philip C. De Witt Hamer, Roelant S. Eijgelaar, Pim J. French, Hendrikus J. Dubbink, Arnaud J. P. E. Vincent, Wiro J. Niessen, Martin J. van den Bent, Marion Smits, Stefan Klein
Accurate characterization of glioma is crucial for clinical decision making.
no code implementations • 3 Oct 2020 • Ruisheng Su, Sandra A. P. Cornelissen, Matthijs van der Sluijs, Adriaan C. G. M. van Es, Wim H. van Zwam, Diederik W. J. Dippel, Geert Lycklama, Pieter Jan van Doormaal, Wiro J. Niessen, Aad van der Lugt, Theo van Walsum
Finally, we quantify the autoTICI score as the ratio of reperfused pixels after EVT.
no code implementations • 15 Sep 2020 • Vikram Venkatraghavan, Stefan Klein, Lana Fani, Leontine S. Ham, Henri Vrooman, M. Kamran Ikram, Wiro J. Niessen, Esther E. Bron
In this work, we determined the effect of APOE alleles on the disease progression timeline of AD using a discriminative event-based model (DEBM).
no code implementations • 26 May 2020 • Bo Li, Marius de Groot, Rebecca M. E. Steketee, Rozanna Meijboom, Marion Smits, Meike W. Vernooij, M. Arfan Ikram, Jiren Liu, Wiro J. Niessen, Esther E. Bron
This 3D end-to-end method is trained to segment 25 WM tracts in aging individuals from a large population-based study (N=9752, 1. 5T MRI).
1 code implementation • 13 May 2020 • Wietske A. P. Bastiaansen, Melek Rousian, Régine P. M. Steegers-Theunissen, Wiro J. Niessen, Anton Koning, Stefan Klein
We propose an unsupervised deep learning method for atlas based registration to achieve segmentation and spatial alignment of the embryonic brain in a single framework.
no code implementations • 12 Apr 2020 • Oliver Werner, Kimberlin M. H. van Wijnen, Wiro J. Niessen, Marius de Groot, Meike W. Vernooij, Florian Dubost, Marleen de Bruijne
We showed that networks optimized using only weak labels reflecting WMH volume generalized better for WMH volume prediction than networks optimized with voxel-wise segmentations of WMH.
no code implementations • 29 Jul 2019 • Kimberlin M. H. van Wijnen, Florian Dubost, Pinar Yilmaz, M. Arfan Ikram, Wiro J. Niessen, Hieab Adams, Meike W. Vernooij, Marleen de Bruijne
We show the potential of this approach to detect enlarged perivascular spaces in white matter on a large brain MRI dataset with an independent test set of 1000 scans.
no code implementations • 8 Mar 2019 • Vikram Venkatraghavan, Florian Dubost, Esther E. Bron, Wiro J. Niessen, Marleen de Bruijne, Stefan Klein
In order to validate the biomarker ordering obtained using nDEBM, we also present a framework for Simulation of Imaging Biomarkers' Temporal Evolution (SImBioTE) that mimics neurodegeneration in brain regions.
no code implementations • 23 Oct 2018 • Gerard Snaauw, Dong Gong, Gabriel Maicas, Anton Van Den Hengel, Wiro J. Niessen, Johan Verjans, Gustavo Carneiro
In this paper, we propose a learning method to train diagnosis models, where our approach is designed to work with relatively small datasets.
1 code implementation • 10 Aug 2018 • Vikram Venkatraghavan, Esther E. Bron, Wiro J. Niessen, Stefan Klein, for the Alzheimer's Disease Neuroimaging Initiative
We evaluated the proposed method on Alzheimer's Disease Neuroimaging Initiative (ADNI) data and compared the results with existing state-of-the-art EBM methods.
1 code implementation • 17 Jul 2017 • Pierre Ambrosini, Daniel Ruijters, Wiro J. Niessen, Adriaan Moelker, Theo van Walsum
We trained the method on images from 182 X-ray sequences from 23 different interventions.