Search Results for author: Yikuan Li

Found 22 papers, 5 papers with code

Enhancing Health Data Interoperability with Large Language Models: A FHIR Study

no code implementations19 Sep 2023 Yikuan Li, Hanyin Wang, Halid Yerebakan, Yoshihisa Shinagawa, Yuan Luo

In this study, we investigated the ability of the large language model (LLM) to enhance healthcare data interoperability.

Language Modelling Large Language Model

Deep Reinforcement Learning for Cost-Effective Medical Diagnosis

1 code implementation20 Feb 2023 Zheng Yu, Yikuan Li, Joseph Kim, Kaixuan Huang, Yuan Luo, Mengdi Wang

In this work, we use reinforcement learning (RL) to find a dynamic policy that selects lab test panels sequentially based on previous observations, ensuring accurate testing at a low cost.

Anomaly Detection Medical Diagnosis +3

A Comparative Study of Pretrained Language Models for Long Clinical Text

1 code implementation27 Jan 2023 Yikuan Li, Ramsey M. Wehbe, Faraz S. Ahmad, Hanyin Wang, Yuan Luo

Objective: Clinical knowledge enriched transformer models (e. g., ClinicalBERT) have state-of-the-art results on clinical NLP (natural language processing) tasks.

Clinical Knowledge Document Classification +5

AD-BERT: Using Pre-trained contextualized embeddings to Predict the Progression from Mild Cognitive Impairment to Alzheimer's Disease

no code implementations7 Nov 2022 Chengsheng Mao, Jie Xu, Luke Rasmussen, Yikuan Li, Prakash Adekkanattu, Jennifer Pacheco, Borna Bonakdarpour, Robert Vassar, Guoqian Jiang, Fei Wang, Jyotishman Pathak, Yuan Luo

Materials and Methods: We identified 3657 patients diagnosed with MCI together with their progress notes from Northwestern Medicine Enterprise Data Warehouse (NMEDW) between 2000-2020.

Multimodal Machine Learning in Precision Health

no code implementations10 Apr 2022 Adrienne Kline, Hanyin Wang, Yikuan Li, Saya Dennis, Meghan Hutch, Zhenxing Xu, Fei Wang, Feixiong Cheng, Yuan Luo

Attempts to improve prediction and resemble the multimodal nature of clinical expert decision-making this has been met in the computational field of machine learning by a fusion of disparate data.

BIG-bench Machine Learning Decision Making

Targeted-BEHRT: Deep learning for observational causal inference on longitudinal electronic health records

no code implementations7 Feb 2022 Shishir Rao, Mohammad Mamouei, Gholamreza Salimi-Khorshidi, Yikuan Li, Rema Ramakrishnan, Abdelaali Hassaine, Dexter Canoy, Kazem Rahimi

The rise of "doubly robust" non-parametric tools coupled with the growth of deep learning for capturing rich representations of multimodal data, offers a unique opportunity to develop and test such models for causal inference on comprehensive electronic health records (EHR).

Causal Inference Decision Making

Clinical-Longformer and Clinical-BigBird: Transformers for long clinical sequences

1 code implementation27 Jan 2022 Yikuan Li, Ramsey M. Wehbe, Faraz S. Ahmad, Hanyin Wang, Yuan Luo

To overcome this, long sequence transformer models, e. g. Longformer and BigBird, were proposed with the idea of sparse attention mechanism to reduce the memory usage from quadratic to the sequence length to a linear scale.

Clinical Knowledge Document Classification +5

Disparities in Social Determinants among Performances of Mortality Prediction with Machine Learning for Sepsis Patients

no code implementations15 Dec 2021 Hanyin Wang, Yikuan Li, Andrew Naidech, Yuan Luo

On the 5, 783 sepsis patients identified by the Sepsis-3 criteria statistically significant performance decreases for mortality prediction were observed when applying the trained machine learning model on Asian and Hispanic patients.

BIG-bench Machine Learning Mortality Prediction

Early Prediction of Mortality in Critical Care Setting in Sepsis Patients Using Structured Features and Unstructured Clinical Notes

no code implementations9 Nov 2021 Jiyoung Shin, Yikuan Li, Yuan Luo

We built and applied several machine learning models to predict the risk of hospital mortality and 30-day mortality in sepsis patients.

Transfer Learning in Electronic Health Records through Clinical Concept Embedding

no code implementations27 Jul 2021 Jose Roberto Ayala Solares, Yajie Zhu, Abdelaali Hassaine, Shishir Rao, Yikuan Li, Mohammad Mamouei, Dexter Canoy, Kazem Rahimi, Gholamreza Salimi-Khorshidi

In this study, we aim to (1) train some of the most prominent disease embedding techniques on a comprehensive EHR data from 3. 1 million patients, (2) employ qualitative and quantitative evaluation techniques to assess these embeddings, and (3) provide pre-trained disease embeddings for transfer learning.

Transfer Learning

Hi-BEHRT: Hierarchical Transformer-based model for accurate prediction of clinical events using multimodal longitudinal electronic health records

no code implementations21 Jun 2021 Yikuan Li, Mohammad Mamouei, Gholamreza Salimi-Khorshidi, Shishir Rao, Abdelaali Hassaine, Dexter Canoy, Thomas Lukasiewicz, Kazem Rahimi

Capturing the whole history of medical encounters is expected to lead to more accurate predictions, but the inclusion of records collected for decades and from multiple resources can inevitably exceed the receptive field of the existing deep learning architectures.

Risk factor identification for incident heart failure using neural network distillation and variable selection

no code implementations17 Feb 2021 Yikuan Li, Shishir Rao, Mohammad Mamouei, Gholamreza Salimi-Khorshidi, Dexter Canoy, Abdelaali Hassaine, Thomas Lukasiewicz, Kazem Rahimi

In this study, we propose two methods, namely, model distillation and variable selection, to untangle hidden patterns learned by an established deep learning model (BEHRT) for risk association identification.

Decision Making Variable Selection

A Comparison of Pre-trained Vision-and-Language Models for Multimodal Representation Learning across Medical Images and Reports

1 code implementation3 Sep 2020 Yikuan Li, Hanyin Wang, Yuan Luo

Joint image-text embedding extracted from medical images and associated contextual reports is the bedrock for most biomedical vision-and-language (V+L) tasks, including medical visual question answering, clinical image-text retrieval, clinical report auto-generation.

Medical Visual Question Answering Question Answering +4

Deep Bayesian Gaussian Processes for Uncertainty Estimation in Electronic Health Records

no code implementations23 Mar 2020 Yikuan Li, Shishir Rao, Abdelaali Hassaine, Rema Ramakrishnan, Yajie Zhu, Dexter Canoy, Gholamreza Salimi-Khorshidi, Thomas Lukasiewicz, Kazem Rahimi

In this paper, we merge features of the deep Bayesian learning framework with deep kernel learning to leverage the strengths of both methods for more comprehensive uncertainty estimation.

Decision Making Gaussian Processes

BEHRT: Transformer for Electronic Health Records

1 code implementation22 Jul 2019 Yikuan Li, Shishir Rao, Jose Roberto Ayala Solares, Abdelaali Hassaine, Dexter Canoy, Yajie Zhu, Kazem Rahimi, Gholamreza Salimi-Khorshidi

Today, despite decades of developments in medicine and the growing interest in precision healthcare, vast majority of diagnoses happen once patients begin to show noticeable signs of illness.

Management

Learning Multimorbidity Patterns from Electronic Health Records Using Non-negative Matrix Factorisation

no code implementations19 Jul 2019 Abdelaali Hassaine, Dexter Canoy, Jose Roberto Ayala Solares, Yajie Zhu, Shishir Rao, Yikuan Li, Mariagrazia Zottoli, Kazem Rahimi, Gholamreza Salimi-Khorshidi

Multimorbidity, or the presence of several medical conditions in the same individual, has been increasing in the population, both in absolute and relative terms.

Benchmarking

Performance Measurement for Deep Bayesian Neural Network

no code implementations20 Mar 2019 Yikuan Li, Yajie Zhu

Deep Bayesian neural network has aroused a great attention in recent years since it combines the benefits of deep neural network and probability theory.

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