DeepCRE: Transforming Drug R&D via AI-Driven Cross-drug Response Evaluation

no code implementations • 6 Mar 2024 • Ting Zhang, Hao Zhou, Hainan Wu, Hanwen Sunchu, Lei Hu, Xiaofang Chen, Suyuan Zhao, Gaochao liu, Chao Sun, Jiahuan Zhang, Yizhen Luo, Peng Liu, Zaiqing Nie, Yushuai Wu

The fields of therapeutic application and drug research and development (R&D) both face substantial challenges, i. e., the therapeutic domain calls for more treatment alternatives, while numerous promising pre-clinical drugs have failed in clinical trials.

Towards Unified AI Drug Discovery with Multiple Knowledge Modalities

no code implementations • 17 Apr 2023 • Yizhen Luo, Xing Yi Liu, Kai Yang, Kui Huang, Massimo Hong, Jiahuan Zhang, Yushuai Wu, Zaiqing Nie

In recent years, AI models that mine intrinsic patterns from molecular structures and protein sequences have shown promise in accelerating drug discovery.

Drug Discovery Knowledge Graphs +2