no code implementations • 6 Feb 2024 • Qing Li, Zhihang Hu, YiXuan Wang, Lei LI, Yimin Fan, Irwin King, Le Song, Yu Li
Central to our focus is the application of FMs to specific biological problems, aiming to guide the research community in choosing appropriate FMs for their research needs.
no code implementations • 14 Jan 2023 • Zhihang Hu, Qinze Yu, Yucheng Guo, Taifeng Wang, Irwin King, Xin Gao, Le Song, Yu Li
While previous methods reported fair performance, their models usually do not take advantage of multi-modal data and they are unable to handle new drugs or cell lines.
no code implementations • 4 Nov 2022 • Haodi Jiang, Qin Li, Zhihang Hu, Nian Liu, Yasser Abduallah, Ju Jing, Genwei Zhang, Yan Xu, Wynne Hsu, Jason T. L. Wang, Haimin Wang
We propose a new deep learning method, named MagNet, to learn from combined LOS magnetograms, Bx and By taken by SDO/HMI along with H-alpha observations collected by the Big Bear Solar Observatory (BBSO), and to generate vector components Bx' and By', which would form vector magnetograms with observed LOS data.
no code implementations • 4 Jul 2022 • Tao Shen, Zhihang Hu, Zhangzhi Peng, Jiayang Chen, Peng Xiong, Liang Hong, Liangzhen Zheng, YiXuan Wang, Irwin King, Sheng Wang, Siqi Sun, Yu Li
When E2Efold-3D is coupled with the experimental techniques, the RNA structure prediction field can be greatly advanced.
1 code implementation • 1 Apr 2022 • Jiayang Chen, Zhihang Hu, Siqi Sun, Qingxiong Tan, YiXuan Wang, Qinze Yu, Licheng Zong, Liang Hong, Jin Xiao, Tao Shen, Irwin King, Yu Li
Non-coding RNA structure and function are essential to understanding various biological processes, such as cell signaling, gene expression, and post-transcriptional regulations.
1 code implementation • 5 Dec 2021 • Xuesong Wang, Zhihang Hu, Tingyang Yu, Ruijie Wang, Yumeng Wei, Juan Shu, Jianzhu Ma, Yu Li
Our approach can efficiently map the above data with high sparsity and noise from different spaces to a low-dimensional manifold in a unified space, making the downstream alignment and integration straightforward.