1 code implementation • 18 Feb 2023 • Xinyan Wang, Ting Jia, Chongyu Wang, Kuan Xu, Zixin Shu, Jian Yu, Kuo Yang, Xuezhong Zhou
In this paper, we construct a biological knowledge graph centered on diseases and genes, and develop an end-to-end Knowledge graph completion model for Disease Gene Prediction using interactional tensor decomposition (called KDGene).
no code implementations • 18 Jul 2022 • Xiao Gan, Zixin Shu, Xinyan Wang, Dengying Yan, Jun Li, Shany ofaim, Réka Albert, XiaoDong Li, Baoyan Liu, Xuezhong Zhou, Albert-László Barabási
We validate our framework with real-world hospital patient data by showing that (1) shorter network distance between symptoms of inpatients correlates with higher relative risk (co-occurrence), and (2) herb-symptom network proximity is indicative of patients' symptom recovery rate after herbal treatment.
1 code implementation • 2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) 2021 • Xin Dong, Yi Zheng, Zixin Shu, Kai Chang, Dengying Yan, Jianan Xia, Qiang Zhu, Kunyu Zhong, Xinyan Wang, Kuo Yang, Xuezhong Zhou
In addition, the comprehensive experiments of TCMPR with different hyper parameters (i. e., feature embedding, feature dimension and feature fusion) that demonstrates that our method has high performance on TCM prescription recommendation and potentially promote clinical diagnosis and treatment of TCM precision medicine.