Extract the answer to the question from the following context. Question: How does the bacteria get acquired resistance? Context: Several molecular mechanisms of antibacterial resistance exist. Intrinsic antibacterial resistance may be part of the genetic makeup of bacterial strains. For example, an antibiotic target may be absent from the bacterial genome. Acquired resistance results from a mutation in the bacterial chromosome or the acquisition of extra-chromosomal DNA. Antibacterial-producing bacteria have evolved resistance mechanisms that have been shown to be similar to, and may have been transferred to, antibacterial-resistant strains. The spread of antibacterial resistance often occurs through vertical transmission of mutations during growth and by genetic recombination of DNA by horizontal genetic exchange. For instance, antibacterial resistance genes can be exchanged between different bacterial strains or species via plasmids that carry these resistance genes. Plasmids that carry several different resistance genes can confer resistance to multiple antibacterials. Cross-resistance to several antibacterials may also occur when a resistance mechanism encoded by a single gene conveys resistance to more than one antibacterial compound.
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Answer: mutation in the bacterial chromosome or the acquisition of extra-chromosomal DNA


Extract the answer to the question from the following context. Question: what is the first branch of the military mentioned? Context: In contrast, the ROK Army defenders were relatively unprepared and ill-equipped. In South to the Naktong, North to the Yalu (1961), R.E. Appleman reports the ROK forces' low combat readiness as of 25 June 1950. The ROK Army had 98,000 soldiers (65,000 combat, 33,000 support), no tanks (they had been requested from the U.S. military, but requests were denied), and a 22-piece air force comprising 12 liaison-type and 10 AT6 advanced-trainer airplanes. There were no large foreign military garrisons in Korea at the time of the invasion, but there were large U.S. garrisons and air forces in Japan.
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Answer: Army


Extract the answer to the question from the following context. Question: When did the Bithynians eventually fall? Context: The Bithynians were a Thracian people living in northwest Anatolia. After Alexander's conquests the region of Bithynia came under the rule of the native king Bas, who defeated Calas, a general of Alexander the Great, and maintained the independence of Bithynia. His son, Zipoetes I of Bithynia maintained this autonomy against Lysimachus and Seleucus I, and assumed the title of king (basileus) in 297 BCE. His son and successor, Nicomedes I, founded Nicomedia, which soon rose to great prosperity, and during his long reign (c. 278 – c. 255 BCE), as well as those of his successors, the kingdom of Bithynia held a considerable place among the minor monarchies of Anatolia. Nicomedes also invited the Celtic Galatians into Anatolia as mercenaries, and they later turned on his son Prusias I, who defeated them in battle. Their last king, Nicomedes IV, was unable to maintain himself against Mithridates VI of Pontus, and, after being restored to his throne by the Roman Senate, he bequeathed his kingdom by will to the Roman republic (74 BCE).
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Answer:
74 BCE