[Q]: Information:  - Aerospace is the human effort in science, engineering and business to fly in the atmosphere of Earth (aeronautics) and surrounding space (astronautics). Aerospace organisations research, design, manufacture, operate, or maintain aircraft and/or spacecraft. Aerospace activity is very diverse, with a multitude of commercial, industrial and military applications.  - Howard Robard Hughes Jr. (December 24, 1905  April 5, 1976) was an American businessman, investor, and philanthropist known during his lifetime as one of the most financially successful individuals in the world. He first made a name for himself as a film producer, and then became an influential figure in the aviation industry. Later in life, he became known for his eccentric behavior and reclusive lifestyle, oddities that were caused in part by a worsening obsessivecompulsive disorder (OCD) and chronic pain from a plane crash.  - Maryland is a state located in the Mid-Atlantic region of the United States, bordering Virginia, West Virginia, and Washington, D.C. to its south and west; Pennsylvania to its north; and Delaware to its east. The state's largest city is Baltimore, and its capital is Annapolis. Among its occasional nicknames are "Old Line State", the "Free State", and the "Chesapeake Bay State". The state is named after Henrietta Maria of France, the wife of Charles I of England.   - Bert Vogelstein ( born 1949 ) is Director of the Ludwig Center , Clayton Professor of Oncology and Pathology and a Howard Hughes Medical Institute investigator at The Johns Hopkins Medical Institutions . A pioneer in the field of cancer genomics , his studies on colorectal cancers revealed that they result from the sequential accumulation of mutations in oncogenes and tumor suppressor genes . These studies now form the paradigm for much of modern cancer research .  - Biomedical research (or experimental medicine) is in general simply known as medical research. It is the basic research (also called "bench science" or "bench research"), applied research, or translational research conducted to aid and support the development of knowledge in the field of medicine.  - The Howard Hughes Medical Institute (HHMI) is a United States non-profit medical research organization based in Chevy Chase, Maryland. It was founded by the American businessman Howard Hughes in 1953. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million. The institute has an endowment of $18.2 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company - an American aerospace firm which was divested to various firms over time.    Given the information, choose the subject and object entities that have the relation of 'place of birth'.
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[A]: bert vogelstein , baltimore


[Q]: Information:  - Svein Knutsson ( Old Norse : Sveinn Knútsson ) c. 1016 -- 1035 , was the son of Cnut the Great , king of Denmark , Norway , and England , and his first wife Ælfgifu of Northampton , a Mercian noblewoman . In 1017 Cnut married Emma of Normandy , but there is no evidence that Ælfgifu was repudiated , and in 1030 Cnut sent her and Svein as regents to rule Norway . However , their rule was considered oppressive by the Norwegians , and they were expelled in 1034 . They imposed new taxes and harsh laws that made them unpopular . In William Shakespeare 's Macbeth , there is a character called `` Sweno , the Norways ' king '' based on Svein .  - Encomium Emmae Reginae or Gesta Cnutonis Regis is an 11th-century Latin encomium in honour of Queen Emma of Normandy. It was written in 1041 or 1042 probably by a monk of St Omer.  - Norway (; Norwegian: (Bokmål) or (Nynorsk); Sami: "Norgga"), officially the Kingdom of Norway, is a sovereign and unitary monarchy whose territory comprises the western portion of the Scandinavian Peninsula plus the island Jan Mayen and the archipelago of Svalbard. The Antarctic Peter I Island and the sub-Antarctic Bouvet Island are dependent territories and thus not considered part of the Kingdom. Norway also lays claim to a section of Antarctica known as Queen Maud Land. Until 1814, the Kingdom included the Faroe Islands (since 1035), Greenland (1261), and Iceland (1262). It also included Shetland and Orkney until 1468. It also included the following provinces, now in Sweden: Jämtland, Härjedalen and Bohuslän.  - King Cnut the Great (Old Norse: "Knútr inn ríki"; c. 995  12 November 1035), also known as Canute, was King of Denmark, England, and Norway, together often referred to as the Anglo-Scandinavian or North Sea Empire. After his death, the deaths of his heirs within a decade, and the Norman conquest of England in 1066, his legacy was mostly forgotten. The medieval historian Norman Cantor stated that he was "the most effective king in Anglo-Saxon history", although Cnut himself was Danish and not a Briton or Anglo-Saxon.  - Emma of Normandy (c. 985  6 March 1052) was a queen consort of England, Denmark and Norway. She was the daughter of Richard I, Duke of Normandy, and his second wife, Gunnora. Through her marriages to Æthelred the Unready (1002-1016) and Cnut the Great (1017-1035), she became the Queen Consort of England, Denmark, and Norway. She was the mother of three sons, Edward the Confessor, Alfred, and Harthacnut, as well as two daughters, Goda of England, and Gunhilda of Denmark. Even after her husbands' deaths Emma remained in the public eye, and continued to participate actively in politics. She is the central figure within the "Encomium Emmae Reginae", a critical source for the history of early 11th-century English politics. As Catherine Karkov notes, Emma is one of the most visually represented early medieval queens.  - Gunhilda of Denmark (1020  18 July 1038), a member of the House of Knýtlinga, was Queen consort of Germany by her marriage with King Henry III of the Salian dynasty from 1036 until her death.     Given the information, choose the subject and object entities that have the relation of 'sister'.
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[A]:
svein knutsson , gunhilda of denmark