Instructions: In this task, you are given a context, a subject, a relation, and many options. Based on the context, from the options select the object entity that has the given relation with the subject. Answer with text (not indexes).
Input: Context: Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual's immune system to develop adaptive immunity to a pathogen. Vaccines can prevent or ameliorate morbidity from infection. When a sufficiently large percentage of a population has been vaccinated, this results in herd immunity. The effectiveness of vaccination has been widely studied and verified; for example, the influenza vaccine, the HPV vaccine, and the chicken pox vaccine. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the restriction of diseases such as polio, measles, and tetanus from much of the world. The World Health Organization (WHO) reports that licensed vaccines are currently available to prevent or contribute to the prevention and control of twenty-five preventable infections., Pathology (from the Greek roots of "pathos", meaning "experience" or "suffering", and "-logia", "study of") is a significant component of the causal study of disease and a major field in modern medicine and diagnosis., A vaccine is a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and keep a record of it so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters. Vaccines can be prophylactic (example: to prevent or ameliorate the effects of a future infection by any natural or "wild" pathogen), or therapeutic (e.g., vaccines against cancer are being investigated)., Tuberculosis (TB) is an infectious disease caused by the bacterium "Mycobacterium tuberculosis" (MTB). Tuberculosis generally affects the lungs, but can also affect other parts of the body. Most infections do not have symptoms; in which case it is known as latent tuberculosis. About 10% of latent infections progress to active disease which, if left untreated, kills about half of those infected. The classic symptoms of active TB are a chronic cough with blood-containing sputum, fever, night sweats, and weight loss. The historical term "consumption" came about due to the weight loss. Infection of other organs can cause a wide range of symptoms.
Tuberculosis is spread through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is based on chest X-rays, as well as microscopic examination and culture of body fluids. Diagnosis of latent TB relies on the tuberculin skin test (TST) or blood tests.
Prevention of TB involves screening those at high risk, early detection and treatment of cases, and vaccination with the bacillus Calmette-Guérin vaccine. Those at high risk include household, workplace, and social contacts of people with active TB. Treatment requires the use of multiple antibiotics over a long period of time. Antibiotic resistance is a growing problem with increasing rates of multiple drug-resistant tuberculosis (MDR-TB).
One-third of the world's population is thought to be infected with TB. New infections occur in about 1% of the population each year. In 2014, there were 9.6 million cases of active TB which resulted in 1.5 million deaths. More than 95% of deaths occurred in developing countries. The number of new cases each year has decreased since 2000. About 80% of people in many Asian and African countries test positive while 510% of people in the United States population tests positive by the tuberculin test. Tuberculosis has been present in humans since ancient times., Genital warts are symptoms of a contagious sexually transmitted disease caused by some types of human papillomavirus (HPV). Warts are the most easily recognized symptom of genital HPV infection. About 90% of those who contract HPV will not develop genital warts, and the remaining 10% who are infected can transmit the virus.
HPV types 6 and 11 are most frequently the cause of genital warts. It is spread through direct skin-to-skin contact, usually during oral, genital, or anal sex with an infected partner. While some types of HPV cause cervical cancer and anal cancers, these are not the same types of HPV that cause genital warts. , " Robert Heinrich Hermann Koch (11 December 1843  27 May 1910) was a celebrated German physician and pioneering microbiologist. As the founder of modern bacteriology, he is known for his role in identifying the specific causative agents of tuberculosis, cholera, and anthrax and for giving experimental support for the concept of infectious disease. In addition to his innovative studies on these diseases, Koch created and improved laboratory technologies and techniques in the field of microbiology, and made key discoveries in public health. His research led to the creation of Kochs postulates, a series of four generalized principles linking specific microorganisms to specific diseases that remain today the "gold standard" in medical microbiology. As a result of his groundbreaking research on tuberculosis, Koch received the Nobel Prize in Physiology or Medicine in 1905., Dissection (from Latin ' "to cut to pieces"; also called anatomization), is the dismembering of the body of a deceased animal or plant to study its anatomical structure. Autopsy is used in pathology and forensic medicine to determine the cause of death in humans. It is carried out by or demonstrated to biology and anatomy students in high school and medical school. Less advanced courses typically focus on smaller subjects, such as small formaldehyde-preserved animals, while the more advanced courses normally use cadavers. Consequently, dissection is typically conducted in a morgue or in an anatomy lab., Tuberculosis verrucosa cutis ( also known as `` Lupus verrucosus , '' `` Prosector 's wart , '' and `` Warty tuberculosis '' ) is a rash of small , red papular nodules in the skin that may appear 2 -- 4 weeks after inoculation by Mycobacterium tuberculosis in a previously infected and immunocompetent individual . It is so called because it was a common occupational disease of prosectors , the preparers of dissections and autopsies . Reinfection by tuberculosis via the skin , therefore , can result from accidental exposure to human tuberculous tissue in physicians , pathologists and laboratory workers ; or to tissues of other infected animals , in veterinarians , butchers , etc. Other names given to this form of skin tuberculosis are anatomist 's wart and verruca necrogenica ( literally , generated by corpses ) . TVC is one of the many forms of cutaneous tuberculosis , such as the tuberculous chancre ( which results from the inoculation in people without immunity , and the reactivation cutaneous tuberculosis ( the most common one , which appears in previously infected patients ) . Other forms of cutaneous tuberculosis are : lupus vulgaris , scrofuloderma , lichen scrofulosorum , erythema induratum and the papulonecrotic tuberculid . It was described by René Laennec in 1826 ., A prosector is a person with the special task of preparing a dissection for demonstration, usually in medical schools or hospitals. Many important anatomists began their careers as prosectors working for lecturers and demonstrators in anatomy and pathology., A diagnosis of latent tuberculosis (LTB), also called latent tuberculosis infection (LTBI) means a patient is infected with "Mycobacterium tuberculosis", but the patient does not have active tuberculosis. Active tuberculosis can be contagious while latent tuberculosis is not, and it is therefore not possible to get TB from someone with latent tuberculosis. The main risk is that approximately 10% of these patients (5% in the first two years after infection and 0.1% per year thereafter) will go on to develop active tuberculosis. This is particularly true, and there is added risk, in particular situations such as medication that suppresses the immune system or advancing age., Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV). Following initial infection, a person may not notice any symptoms or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged period with no symptoms. As the infection progresses, it interferes more with the immune system, increasing the risk of common infections like tuberculosis, as well as other opportunistic infections, and tumors that rarely affect people who have working immune systems. These late symptoms of infection are referred to as AIDS. This stage is often also associated with weight loss.
HIV is spread primarily by unprotected sex (including anal and oral sex), contaminated blood transfusions, hypodermic needles, and from mother to child during pregnancy, delivery, or breastfeeding. Some bodily fluids, such as saliva and tears, do not transmit HIV. Methods of prevention include safe sex, needle exchange programs, treating those who are infected, and male circumcision. Disease in a baby can often be prevented by giving both the mother and child antiretroviral medication. There is no cure or vaccine; however, antiretroviral treatment can slow the course of the disease and may lead to a near-normal life expectancy. Treatment is recommended as soon as the diagnosis is made. Without treatment, the average survival time after infection is 11 years.
In 2015 about 36.7 million people were living with HIV and it resulted in 1.1 million deaths. Most of those infected live in sub-Saharan Africa. Between its discovery and 2014 AIDS has caused an estimated 39 million deaths worldwide. HIV/AIDS is considered a pandemica disease outbreak which is present over a large area and is actively spreading. HIV is believed to have originated in west-central Africa during the late 19th or early 20th century. AIDS was first recognized by the United States Centers for Disease Control and Prevention (CDC) in 1981 and its causeHIV infectionwas identified in the early part of the decade.
HIV/AIDS has had a great impact on society, both as an illness and as a source of discrimination. The disease also has large economic impacts. There are many misconceptions about HIV/AIDS such as the belief that it can be transmitted by casual non-sexual contact. The disease has become subject to many controversies involving religion including the Catholic Church's decision not to support condom use as prevention. It has attracted international medical and political attention as well as large-scale funding since it was identified in the 1980s., Warts are typically small, rough, and hard growths that are similar in color to the rest of the skin. They typically do not result in symptoms except when on the bottom of the feet where they may be painful. While they usually occur on the hands and feet they can also affect other locations. One or many warts may appear. They are not cancerous.
Warts are caused by infection with a type of human papillomavirus (HPV). Factors that increase the risk include use of public showers, working with meat, eczema, and a low immune system. The virus is believed to enter the body through skin that has been damaged slightly. A number of types exist including: common warts, plantar warts, filiform warts, and genital warts. Genital warts are often sexually transmitted.
Without treatment, most types of warts resolve in months to years. A number of treatments may speed resolution including salicylic acid applied to the skin and cryotherapy. In those who are otherwise healthy they do not typically result in significant problems. Treatment of genital warts differ from that of other types.
Warts are very common with most people being infected at some point in time. The estimated current rate of non-genital warts among the generally population is 113%. They are more common among young people. Estimated rates of genital warts in sexually active women is 12%. Warts have been described at least as far back as 400 BC by Hippocrates., A medical school is a tertiary educational institutionor part of such an institutionthat teaches medicine, and awards a professional degree for physicians and surgeons. Such medical degrees include the Bachelor of Medicine, Bachelor of Surgery (MBBS, MBChB, BMBS), Doctor of Medicine (MD), or Doctor of Osteopathic Medicine (DO). Many medical schools offer additional degrees, such as a Doctor of Philosophy, Master's degree, a physician assistant program, or other post-secondary education., Sputum is mucus and is the name used for the coughed-up material (phlegm) from the lower airways (trachea and bronchi). This process is known as sputilization. In medicine, sputum samples are usually used for naked eye exam, microbiological investigations of respiratory infections and cytological investigations of respiratory systems. It is critical that the patient not give a specimen that includes any mucoid material from the interior of the nose. Naked eye exam of sputum can be done at home by a patient in order to note the various colors (see below). Any hint of yellow color suggests an airway infection (but does not indicate between the types of organisms causing it). Such color hints are best detected when the sputum is viewed on a very white background such as white paper, a white pot, or a white sink surface. The more intense the yellow color, the more likely it is a bacterial infection (bronchitis, bronchopneumonia, or pneumonia)., Mycobacterium tuberculosis is an obligate pathogenic bacterial species in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, "M. tuberculosis" has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining and as a result "M. tuberculosis" can appear either Gram-negative or Gram-positive. Acid-fast stains such as Ziehl-Neelsen, or fluorescent stains such as auramine are used instead to identify M. tuberculosis with a microscope. The physiology of "M. tuberculosis" is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the tuberculin skin test, acid-fast stain, culture, and polymerase chain reaction., Subject: prosector's wart, Relation: medical_specialty, Options: (A) infection (B) infectious disease (C) pathology (D) surgery
Output:
infectious disease