Q:Information:  - Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a category of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim to prolong life or to reduce symptoms (palliative chemotherapy). Chemotherapy is one of the major categories of medical oncology (the medical discipline specifically devoted to pharmacotherapy for cancer).  - The Mississippi River is the chief river of the largest drainage system on the North American continent. Flowing entirely in the United States (although its drainage basin reaches into Canada), it rises in northern Minnesota and meanders slowly southwards for to the Mississippi River Delta at the Gulf of Mexico. With its many tributaries, the Mississippi's watershed drains all or parts of 31 U.S. states and 2 Canadian provinces between the Rocky and Appalachian Mountains. The Mississippi ranks as the fourth longest and fifteenth largest river in the world by discharge. The river either borders or passes through the states of Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana.  - Menopause, also known as the climacteric, is the time in most women's lives when menstrual periods stop permanently, and they are no longer able to bear children. Menopause typically occurs between 49 and 52 years of age. Medical professionals often define menopause as having occurred when a woman has not had any vaginal bleeding for a year. It may also be defined by a decrease in hormone production by the ovaries. In those who have had surgery to remove their uterus but they still have ovaries, menopause may be viewed to have occurred at the time of the surgery or when their hormone levels fell. Following the removal of the uterus, symptoms typically occur earlier, at an average of 45 years of age. Before menopause, a woman's periods typically become irregular, which means that periods may be longer or shorter in duration or be lighter or heavier in the amount of flow. During this time, women often experience hot flashes; these typically last from 30 seconds to ten minutes and may be associated with shivering, sweating, and reddening of the skin. Hot flashes often stop occurring after a year or two. Other symptoms may include vaginal dryness, trouble sleeping, and mood changes. The severity of symptoms varies between women. While menopause is often thought to be linked to an increase in heart disease, this primarily occurs due to increasing age and does not have a direct relationship with menopause. In some women, problems that were present like endometriosis or painful periods will improve after menopause. Menopause is usually a natural change. It can occur earlier in those who smoke tobacco. Other causes include surgery that removes both ovaries or some types of chemotherapy. At the physiological level, menopause happens because of a decrease in the ovaries' production of the hormones estrogen and progesterone. While typically not needed, a diagnosis of menopause can be confirmed by measuring hormone levels in the blood or urine. Menopause is the opposite of menarche, the time when a girl's periods...  - Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is therapy using ionizing radiation, generally as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology.  - Lobular carcinoma is a form of tumor which primarily affects the lobules of a gland.  - A census is the procedure of systematically acquiring and recording information about the members of a given population. It is a regularly occurring and official count of a particular population. The term is used mostly in connection with national population and housing censuses; other common censuses include agriculture, business, and traffic censuses. The United Nations defines the essential features of population and housing censuses as "individual enumeration, universality within a defined territory, simultaneity and defined periodicity", and recommends that population censuses be taken at least every 10 years. United Nations recommendations also cover census topics to be collected, official definitions, classifications and other useful information to co-ordinate international practice.  - Bone pain (also known medically by several other names) is pain coming from a bone. It occurs as a result of a wide range of diseases and/or physical conditions and may severely impair the quality of life for patients who suffer from it. Bone pain belongs to the class of deep somatic pain, often experienced as a dull pain that cannot be localized accurately by the patient. This is in contrast with the pain which is mediated by superficial receptors in, e.g., the skin. Bone pain can have several possible causes ranging from extensive physical stress to serious diseases such as cancer. For many years it has been known that bones are innervated with sensory neurons. Yet their exact anatomy remained obscure due to the contrasting physical properties of bone and neural tissue. More recently, it is becoming clear what types of nerves innervated which sections of bone. The periosteal layer of bone tissue is highly pain-sensitive and an important cause of pain in several disease conditions causing bone pain, like fractures, osteoarthritis, etc. However, in certain diseases the endosteal and haversian nerve supply seems to play an important role, e.g. in osteomalacia, osteonecrosis, and other bone diseases. Thus there are several types of bone pain, each with many potential sources or origins of cause.  - The breast is one of two prominences located on the upper ventral region of the torso of female primates. In females, it serves as the mammary gland, which produces and secretes milk and feeds infants. Both females and males develop breasts from the same embryological tissues. At puberty, estrogens, in conjunction with growth hormone, cause breast development. Males do not develop pronounced or physiologically matured breasts because their bodies produce lower levels of estrogens and higher levels of androgens, namely testosterone, which suppress the effects of estrogens in developing breast tissue. The breasts of females are typically far more prominent than those of males.  - Raloxifene (marketed as Evista by Eli Lilly and Company) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.  - Canadian football is a form of gridiron football played in Canada in which two teams of 12 players each compete for territorial control of a field of play long and wide attempting to advance a pointed prolate spheroid ball into the opposing team's scoring area (end zone).  - The Atlanta Falcons are a professional American football team based in Atlanta, Georgia. The Falcons compete in the National Football League (NFL) as a member club of the league's National Football Conference (NFC) South division. The Falcons joined the NFL in 1965 as an expansion team, after the NFL offered then-owner Rankin Smith a franchise to keep him from joining the rival American Football League (AFL). The AFL instead granted a franchise to Miami (the Miami Dolphins). The Falcons are tied with the Dolphins (who also began play in 1966) for being the second-oldest NFL franchise in the Deep South, and are the second-oldest NFC team in that region, after the Dallas Cowboys.  - A quarterback (commonly abbreviated to QB) is a position in American and Canadian football. Quarterbacks are members of the offensive team and line up directly behind the offensive line. In modern American football, the quarterback is usually considered the leader of the offensive team, and is often responsible for calling the play in the huddle.  - Breast-conserving surgery (BCS, also known as breast conservation surgery and segmental mastectomy) is a less radical cancer surgery than mastectomy. Breast-conserving surgery, as in a lumpectomy removes part of the breast tissue during surgery, as opposed to the entire breast.  - In physics, radiation is the emission or transmission of energy in the form of waves or particles through space or through a material medium. This includes:  - A hormone (from the Greek participle ) is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour. Hormones have diverse chemical structures, mainly of 3 classes: eicosanoids, steroids, and amino acid derivatives (amines, peptides, and proteins). The glands that secrete hormones comprise the endocrine signaling system. The term hormone is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signalling) or nearby cells (paracrine signalling).  - Shortness of breath, also known as dyspnea, is a feeling like one cannot breathe well enough. The American Thoracic Society defines it as "a subjective experience of breathing discomfort that consists of qualitatively distinct sensations that vary in intensity", and recommends evaluating dyspnea by assessing the intensity of the distinct sensations, the degree of distress involved, and its burden or impact on activities of daily living. Distinct sensations include effort/work, chest tightness, and air hunger (the feeling of not enough oxygen).  - The National Football League (NFL) is a professional American football league consisting of 32 teams, divided equally between the National Football Conference (NFC) and the American Football Conference (AFC). The NFL is one of the four major professional sports leagues in North America, and the highest professional level of American football in the world. The NFL's 17-week regular season runs from the week after Labor Day to the week after Christmas, with each team playing 16 games and having one bye week. Following the conclusion of the regular season, six teams from each conference (four division winners and two wild card teams) advance to the playoffs, a single-elimination tournament culminating in the Super Bowl, played between the champions of the NFC and AFC.  - Deanna Tynes Favre ( born December 28 , 1968 in Kiln , Mississippi ) is an American activist and the wife of NFL quarterback Brett Favre . She was diagnosed with breast cancer in 2004 , and later became an activist in the fight against the disease . She founded the Deanna Favre Hope Foundation to raise money and awareness for women around the country .  - A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist involving extraction of sample cells or tissues for examination to determine the presence or extent of a disease. The tissue is generally examined under a microscope by a pathologist, and can also be analyzed chemically. When an entire lump or suspicious area is removed, the procedure is called an excisional biopsy. When only a sample of tissue is removed with preservation of the histological architecture of the tissues cells, the procedure is called an incisional biopsy or core biopsy. When a sample of tissue or fluid is removed with a needle in such a way that cells are removed without preserving the histological architecture of the tissue cells, the procedure is called a needle aspiration biopsy. Biopsies are most commonly performed for insight into possible cancerous and inflammatory conditions.  - Hormone replacement therapy (HRT) is any form of hormone therapy wherein the patient, in the course of medical treatment, receives hormones, either to supplement a lack of naturally occurring hormones or to substitute other hormones for naturally occurring hormones. Common forms of hormone replacement therapy include:  - Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, fluid coming from the nipple, or a red scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include being female, obesity, lack of physical exercise, drinking alcohol, hormone replacement therapy during menopause, ionizing radiation, early age at first menstruation, having children late or not at all, older age, and family history. About 510% of cases are due to genes inherited from a person's parents, including BRCA1 and BRCA2 among others. Breast cancer most commonly develops in cells from the lining of milk ducts and the lobules that supply the ducts with milk. Cancers developing from the ducts are known as ductal carcinomas, while those developing from lobules are known as lobular carcinomas. In addition, there are more than 18 other sub-types of breast cancer. Some cancers, such as ductal carcinoma in situ, develop from pre-invasive lesions. The diagnosis of breast cancer is confirmed by taking a biopsy of the concerning lump. Once the diagnosis is made, further tests are done to determine if the cancer has spread beyond the breast and which treatments it may respond to. The balance of benefits versus harms of breast cancer screening is controversial. A 2013 Cochrane review stated that it is unclear if mammographic screening does more good or harm. A 2009 review for the US Preventive Services Task Force found evidence of benefit in those 40 to 70 years of age, and the organization recommends screening every two years in women 50 to 74 years old. The medications tamoxifen or raloxifene may be used in an effort to prevent breast cancer in those who are at high risk of developing it. Surgical removal of both breasts is another preventative measure in some high risk women. In those who have been diagnosed with...  - A lymph node or lymph gland, is an ovoid or kidney-shaped organ of the lymphatic system, and of the adaptive immune system, that is widely present throughout the body. They are linked by the lymphatic vessels as a part of the circulatory system. Lymph nodes are major sites of B and T lymphocytes, and other white blood cells. Lymph nodes are important for the proper functioning of the immune system, acting as filters for foreign particles and cancer cells. Lymph nodes do not have a detoxification function, which is primarily dealt with by the liver and kidneys.  - A census-designated place (CDP) is a concentration of population defined by the United States Census Bureau for statistical purposes only. CDPs have been used in each decennial census since 1980 as the counterparts of incorporated places, such as cities, towns, and villages for the purposes of gathering and correlating statistical data. CDPs are populated areas that generally include one officially designated but currently unincorporated small community, for which the CDP is named, plus surrounding inhabited countryside of varying dimensions and, occasionally, other, smaller unincorporated communities as well. CDPs include small rural communities, colonias located along the U.S. border with Mexico, and unincorporated resort and retirement communities and their environs.  - Ductal carcinoma in situ (DCIS), also known as intraductal carcinoma, is a pre-cancerous or non-invasive cancerous lesion of the breast. DCIS is classified as Stage 0. It rarely produces symptoms or a breast lump one can feel, and is usually detected through screening mammography. In DCIS, abnormal cells are found in the lining of one or more milk ducts in the breast. "In situ" means "in place" and refers to the fact that the abnormal cells have not moved out of the mammary duct and into any of the surrounding tissues in the breast ("pre-cancerous" refers to the fact that it has not yet become an invasive cancer). In some cases, DCIS may become invasive and spread to other tissues, but there is no way of determining which lesions will remain stable without treatment, and which will go on to become invasive. DCIS encompasses a wide spectrum of diseases ranging from low-grade lesions that are not life-threatening to high-grade (i.e. potentially highly aggressive) lesions. DCIS has been classified according to the architectural pattern of the cells (solid, cribriform, papillary, and micropapillary), tumor grade (high, intermediate, and low grade), and the presence or absence of comedo histology. DCIS can be detected on mammograms by examining tiny specks of calcium known as microcalcifications. Since suspicious groups of microcalcifications can appear even in the absence of DCIS, a biopsy may be necessary for diagnosis. About 2030% of those who do not receive treatment develop breast cancer. It is the most common type of pre-cancer in women. There is some disagreement as to whether, for statistical purposes, it should be counted as a cancer: some include DCIS when calculating breast cancer statistics while others do not.  - In sport, a huddle is an action of a team gathering together, usually in a tight circle, to strategize, motivate or celebrate. It is a popular strategy for keeping opponents insulated from sensitive information, and acts as a form of insulation when the level of noise in the venue is such that normal on-field communication is difficult. Commonly the leader of the huddle is the team captain and it is the captain who will try to inspire his fellow team members to achieve success. Similarly after an event a huddle may take place to congratulate one another for the teams success, or to commiserate a defeat. The term "huddle" can be used as a verb as in "huddling up".  - The Green Bay Packers are a professional American football team based in Green Bay, Wisconsin. The Packers compete in the National Football League (NFL) as a member club of the league's National Football Conference (NFC) North division. They are also the third-oldest franchise in the NFL, organized and starting play in 1919. It is the only non-profit, community-owned major league professional sports team based in the United States. Home games are played at Lambeau Field.  - Surgery (from the "cheirourgik" (composed of , "hand", and , "work"), via , meaning "hand work") is an ancient medical specialty that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, to help improve bodily function or appearance or to repair unwanted ruptured areas (for example, a perforated ear drum).  - Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment (pharmacotherapy) for cancer, others being hormonal therapy and cytotoxic chemotherapy. As a form of molecular medicine, targeted therapy blocks the growth of cancer cells by interfering with specific targeted molecules needed for carcinogenesis and tumor growth, rather than by simply interfering with all rapidly dividing cells (e.g. with traditional chemotherapy). Because most agents for targeted therapy are biopharmaceuticals, the term "biologic therapy" is sometimes synonymous with "targeted therapy" when used in the context of cancer therapy (and thus distinguished from chemotherapy, that is, cytotoxic therapy). However, the modalities can be combined; antibody-drug conjugates combine biologic and cytotoxic mechanisms into one targeted therapy.  - Breast reconstruction is the rebuilding of a breast, usually in women. It involves using autologous tissue or prosthetic material to construct a natural-looking breast. Often this includes the reformation of a natural-looking areola and nipple. This procedure involves the use of implants or relocated flaps of the patient's own tissue.  - Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health. People are generally considered obese when their body mass index (BMI), a measurement obtained by dividing a person's weight by the square of the person's height, is over , with the range defined as overweight. Some East Asian countries use lower values. Obesity increases the likelihood of various diseases, particularly heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity is most commonly caused by a combination of excessive food intake, lack of physical activity, and genetic susceptibility. A few cases are caused primarily by genes, endocrine disorders, medications, or mental illness. The view that obese people eat little yet gain weight due to a slow metabolism is not generally supported. On average, obese people have a greater energy expenditure than their thin counterparts due to the energy required to maintain an increased body mass. Obesity is mostly preventable through a combination of social changes and personal choices. Changes to diet and exercising are the main treatments. Diet quality can be improved by reducing the consumption of energy-dense foods, such as those high in fat and sugars, and by increasing the intake of dietary fiber. Medications may be taken, along with a suitable diet, to reduce appetite or decrease fat absorption. If diet, exercise, and medication are not effective, a gastric balloon or surgery may be performed to reduce stomach volume or bowel length, leading to feeling full earlier or a reduced ability to absorb nutrients from food. Obesity is a leading preventable cause of death worldwide, with increasing rates in adults and children. In 2014, 600 million adults (13%) and 42 million children under the age of five were obese. Obesity is more common in women than men. Authorities view it as one of the most serious public health problems of the 21st century. Obesity is stigmatized in much of...  - Ionizing radiation (ionising radiation) is radiation that carries enough energy to free electrons from atoms or molecules, thereby ionizing them. Ionizing radiation is made up of energetic subatomic particles, ions or atoms moving at high speeds (usually greater than 1% of the speed of light), and electromagnetic waves on the high-energy end of the electromagnetic spectrum.  - Brett Lorenzo Favre (born October 10, 1969) is a former American football quarterback who spent the majority of his career with the Green Bay Packers of the National Football League (NFL). He was a 20-year veteran of the NFL, having played quarterback for the Atlanta Falcons (1991), Green Bay Packers (19922007), New York Jets (2008), and Minnesota Vikings (20092010). Favre was the first quarterback in NFL history to pass for 500 touchdowns, throw for over 70,000 yards, over 6,000 completions, and over 10,000 pass attempts.  - American football, referred to as football in the United States and Canada, and also known as gridiron, is a sport played by two teams of eleven players on a rectangular field with goalposts at each end. The offense, the team with control of the oval-shaped football, attempts to advance down the field by running with or passing the ball, while the team without control of the ball, the defense, aims to stop their advance and take control of the ball for themselves. The offense must advance at least ten yards in four downs, or plays, or else they turn over the football to the opposing team; if they succeed, they are given a new set of four downs. Points are primarily scored by advancing the ball into the opposing team's end zone for a touchdown or kicking the ball through the opponent's goalposts for a field goal. The team with the most points at the end of a game wins.  - The New York Jets are a professional American football team located in the New York metropolitan area. The Jets compete in the National Football League (NFL) as a member club of the league's American Football Conference (AFC) East division. The team is headquartered in Florham Park, New Jersey. In a unique arrangement for the league, the Jets share MetLife Stadium in East Rutherford, New Jersey with the New York Giants. The franchise is legally and corporately registered as New York Jets, LLC.  - Breast cancer screening is the medical screening of asymptomatic, apparently healthy women for breast cancer in an attempt to achieve an earlier diagnosis. The assumption is that early detection will improve outcomes. A number of screening tests have been employed, including clinical and self breast exams, mammography, genetic screening, ultrasound, and magnetic resonance imaging.  - The Minnesota Vikings are an American football team based in Minneapolis, Minnesota. The Vikings joined the National Football League (NFL) as an expansion team in 1960, and first took the field for the 1961 season. The team competes in the National Football Conference (NFC) North division; before that, the Vikings were in the NFC Central, and before that they were in the NFL's Western Conference Central Division. The team has played in four Super Bowl games, but lost each one. The team plays its home games at U.S. Bank Stadium in the Downtown East section of Minneapolis.  - Mastectomy (from Greek "breast" and "ektomia" "cutting out") is the medical term for the surgical removal of one or both breasts, partially or completely.  - Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Not all tumors are cancerous; benign tumors do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss and a change in bowel movements. While these symptoms may indicate cancer, they may have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% is due to obesity, poor diet, lack of physical activity and drinking alcohol. Other factors include certain infections, exposure to ionizing radiation and environmental pollutants. In the developing world nearly 20% of cancers are due to infections such as hepatitis B, hepatitis C and human papillomavirus (HPV). These factors act, at least partly, by changing the genes of a cell. Typically many genetic changes are required before cancer develops. Approximately 510% of cancers are due to inherited genetic defects from a person's parents. Cancer can be detected by certain signs and symptoms or screening tests. It is then typically further investigated by medical imaging and confirmed by biopsy. Many cancers can be prevented by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat, and avoiding too much sunlight exposure. Early detection through screening is useful for cervical and colorectal cancer. The benefits of screening in breast cancer are controversial. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy, and targeted therapy. Pain and symptom management are an important part of care. Palliative care is particularly important in people with advanced disease. The chance of survival depends on the type of cancer and extent of disease at the start of treatment. In children under 15 at...  - Mississippi is a state in the southern region of the United States, with part of its southern border formed by the Gulf of Mexico. Its western border is formed by the Mississippi River.  - The Gulf of Mexico is an ocean basin largely surrounded by the North American continent. It is bounded on the northeast, north and northwest by the Gulf Coast of the United States, on the southwest and south by Mexico, and on the southeast by Cuba. The U.S. states of Alabama, Florida, Louisiana, Mississippi and Texas border the Gulf on the north, which are often referred to as the "Third Coast" in comparison with the U.S. Atlantic and Pacific coasts, or sometimes the "south coast", in juxtaposition to the Great Lakes region being the "north coast." One of the gulf's seven main areas is the Gulf of Mexico basin.  - Kiln is a census-designated place (CDP) in Hancock County, Mississippi. It is part of the GulfportBiloxi, Mississippi Metropolitan Statistical Area. The population was 2,238 at the 2010 census.    Given the information above, choose from the list below the object entity that exhibits the relation 'place of birth' with the subject 'deanna favre'.  Choices: - africa  - alabama  - american football  - atlanta  - canada  - canadian  - central  - cochrane  - date  - east rutherford  - georgia  - green  - green bay  - gulfport  - hancock  - iowa  - jersey  - kentucky  - light  - made  - miami  - minnesota  - mississippi  - missouri  - most  - new jersey  - new york  - normal  - of  - once  - oral  - pacific  - rates  - side  - southeast  - southern region  - tennessee  - time  - wisconsin  - york
A:
gulfport