Please answer the following question: Information:  - Canadian Institutes of Health Research (CIHR) is the major federal agency responsible for funding health research in Canada. It is the successor to the Medical Research Council of Canada. It aims to create new health knowledge, and to translate that knowledge from the research setting into real world applications. The CIHR was created by an Act of Parliament on June 7, 2000; bringing together existing government activities. In 2009-2010, CIHR's budget was just over 1 billion dollars.  - The Entrez Global Query Cross-Database Search System is a federated search engine, or web portal that allows users to search many discrete health sciences databases at the National Center for Biotechnology Information (NCBI) website. The NCBI is a part of the National Library of Medicine (NLM), which is itself a department of the National Institutes of Health (NIH), which in turn is a part of the United States Department of Health and Human Services. The name "Entrez" (a greeting meaning "Come in!" in French) was chosen to reflect the spirit of welcoming the public to search the content available from the NLM.  - In computing, Extensible Markup Language (XML) is a markup language that defines a set of rules for encoding documents in a format that is both human-readable and machine-readable. The W3C's XML 1.0 Specification and several other related specificationsall of them free open standardsdefine XML.  - PubMed Central (PMC) is a free digital repository that archives publicly accessible full-text scholarly articles that have been published within the biomedical and life sciences journal literature. As one of the major research databases within the suite of resources that have been developed by the National Center for Biotechnology Information (NCBI), PubMed Central is much more than just a document repository. Submissions into PMC undergo an indexing and formatting procedure which results in enhanced metadata, medical ontology, and unique identifiers which all enrich the XML structured data for each article on deposit. Content within PMC can easily be interlinked to many other NCBI databases and accessed via Entrez search and retrieval systems, further enhancing the public's ability to freely discover, read and build upon this portfolio of biomedical knowledge.  - Europe PubMed Central ( Europe PMC ) is an on - line database that offers free access to a large and growing collection of biomedical research literature . It was known as UK PubMed Central until 1 November 2012 . The Europe PMC project was originally launched in 2007 as the first `` mirror '' site to PMC , which aims to provide international preservation of the open and free - access biomedical and life sciences literature . It forms part of a network of PMC International ( PMCI ) repositories that includes PubMed Central Canada . Europe PMC is not an exact `` mirror '' of the PMC database but has developed some different features . On February 15 , 2013 , CiteXplore was subsumed under Europe PubMed Central . The resource is managed and developed by the European Molecular Biology Laboratory - European Bioinformatics Institute ( EMBL - EBI ) , along with The British Library , Jisc , NaCTeM and the University of Manchester on behalf of an alliance of 27 biomedical and life sciences research funders , led by the Wellcome Trust . The Europe PMC funders group requires that articles describing the results of biomedical and life sciences research they have supported be made freely available in Europe PMC within 6 months of publication to maximise the impact of the work that they fund .  - The NCBI houses a series of databases relevant to biotechnology and biomedicine and an important resource for bioinformatics tools and services. Major databases include GenBank for DNA sequences and PubMed, a bibliographic database for the biomedical literature. Other databases include the NCBI Epigenomics database. All these databases are available online through the Entrez search engine.  - PubMed is a free search engine accessing primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institutes of Health maintains the database as part of the Entrez system of information retrieval.  - PubMed Central Canada (PMC Canada) is a Canadian national digital repository of peer-reviewed health and life sciences literature. It joins Europe PubMed Central (formerly UK PubMed Central) as a member of the PubMed Central International network. PMC Canada is a partnership between the Canadian Institutes of Health Research (CIHR), the Canada Institute for Scientific and Technical Information (NRC-CISTI, the Canadian National Science Library), and the United States National Library of Medicine (NLM).    Given the information, choose the subject and object entities that have the relation of 'instance of'.
A:
europe pubmed central , website