In this task, you are given a context, a subject, a relation, and many options. Based on the context, from the options select the object entity that has the given relation with the subject. Answer with text (not indexes).
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Question: Context: An American comic book is a thin (typically 32-page) periodical containing primarily comics content., Ruby Thursday ( Thursday Rubinstein ) is a fictional character appearing in American comic books published by Marvel Comics . She is usually depicted as a member of the Headmen . She is named for the Rolling Stones song , `` Ruby Tuesday '' ., A supervillain is a variant of the villainous stock character archetype commonly found in American comic books and sometimes possesses superhuman abilities. A supervillain is the antithesis of a superhero., The Walt Disney Company, commonly known as Disney, is an American diversified multinational mass media and entertainment conglomerate headquartered at the Walt Disney Studios in Burbank, California. It is the world's second largest media conglomerate in terms of revenue, after Comcast. Disney was founded on October 16, 1923, by brothers Walt Disney and Roy O. Disney as the Disney Brothers Cartoon Studio, and established itself as a leader in the American animation industry before diversifying into live-action film production, television, and theme parks. The company also operated under the names The Walt Disney Studio, then Walt Disney Productions. Taking on its current name in 1986, it expanded its existing operations and also started divisions focused upon theater, radio, music, publishing, and online media., Marvel Comics is the common name and primary imprint of Marvel Worldwide Inc., formerly Marvel Publishing, Inc. and Marvel Comics Group, an American publisher of comic books and related media. In 2009, The Walt Disney Company acquired Marvel Entertainment, Marvel Worldwide's parent company., The Headmen is a group of fictional supervillains appearing in American comic books published by Marvel Comics., Marvel Entertainment, LLC (formerly Marvel Enterprises and Toy Biz, Inc. and marketed and stylized as MARVEL) is an American entertainment company founded in June 1998, merging Marvel Entertainment Group, Inc. and ToyBiz. The company is a wholly owned subsidiary of The Walt Disney Company, and is mainly known for its Marvel Comics, Marvel Animation and Marvel Television units. Marvel Studios, formerly under the "Marvel" umbrella, became a subsidiary of The Walt Disney Studios, where it develops and produces a shared universe that shares continuity with shows produced by the television unit., Subject: ruby thursday, Relation: instance_of, Options: (A) action (B) american comic book (C) archetype (D) character (E) comic (F) common name (G) company (H) entertainment (I) group (J) industry (K) june (L) mass (M) mass media (N) name (O) page (P) publisher (Q) publishing (R) stock character (S) studio (T) superhero (U) supervillain (V) television (W) theater (X) toy

Answer: supervillain


Question: Context: Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a category of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim to prolong life or to reduce symptoms (palliative chemotherapy). Chemotherapy is one of the major categories of medical oncology (the medical discipline specifically devoted to pharmacotherapy for cancer)., A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist involving extraction of sample cells or tissues for examination to determine the presence or extent of a disease. The tissue is generally examined under a microscope by a pathologist, and can also be analyzed chemically. When an entire lump or suspicious area is removed, the procedure is called an excisional biopsy. When only a sample of tissue is removed with preservation of the histological architecture of the tissues cells, the procedure is called an incisional biopsy or core biopsy. When a sample of tissue or fluid is removed with a needle in such a way that cells are removed without preserving the histological architecture of the tissue cells, the procedure is called a needle aspiration biopsy. Biopsies are most commonly performed for insight into possible cancerous and inflammatory conditions., Xeroderma pigmentosum (XP) is a rare autosomal recessive genetic disorder of DNA repair in which the ability to repair damage caused by ultraviolet (UV) light is deficient. In extreme cases, "all" exposure to sunlight must be forbidden, no matter how small; as such, individuals with the disease are often colloquially referred to as "Moon child". Multiple basal cell carcinomas (basaliomas) and other skin malignancies frequently occur at a young age in those with XP; metastatic malignant melanoma and squamous cell carcinoma are the two most common causes of death in XP victims. This disease is present in both genders and in all races, with an incidence of 1:250,000 in the United States. XP is roughly six times more common in Japanese people than in other groups., Ivan Yevhenovych Vyshnevskyi ( Ukrainian :    , Russian :    ; born 21 February 1957 in the village of Chortoryia ( today 's Myrolyubivka , Ternopil Raion ) ; died 11 May 1996 in Dnipropetrovsk of melanoma ) was a Ukrainian footballer . He earned 6 caps for the USSR national football team , making his debut on 25 January 1985 in a friendly against Yugoslavia . He was selected for the UEFA Euro 1988 squad , but did not play in any games at the tournament . He is from the region that once belonged to Winiowiecki family that had estates near Zboriv where the village of Vyshnivets is located ., Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Not all tumors are cancerous; benign tumors do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss and a change in bowel movements. While these symptoms may indicate cancer, they may have other causes. Over 100 types of cancers affect humans.
Tobacco use is the cause of about 22% of cancer deaths. Another 10% is due to obesity, poor diet, lack of physical activity and drinking alcohol. Other factors include certain infections, exposure to ionizing radiation and environmental pollutants. In the developing world nearly 20% of cancers are due to infections such as hepatitis B, hepatitis C and human papillomavirus (HPV). These factors act, at least partly, by changing the genes of a cell. Typically many genetic changes are required before cancer develops. Approximately 510% of cancers are due to inherited genetic defects from a person's parents. Cancer can be detected by certain signs and symptoms or screening tests. It is then typically further investigated by medical imaging and confirmed by biopsy.
Many cancers can be prevented by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat, and avoiding too much sunlight exposure. Early detection through screening is useful for cervical and colorectal cancer. The benefits of screening in breast cancer are controversial. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy, and targeted therapy. Pain and symptom management are an important part of care. Palliative care is particularly important in people with advanced disease. The chance of survival depends on the type of cancer and extent of disease at the start of treatment. In children under 15 at diagnosis the five-year survival rate in the developed world is on average 80%. For cancer in the United States the average five-year survival rate is 66%.
In 2012 about 14.1 million new cases of cancer occurred globally (not including skin cancer other than melanoma). It caused about 8.2 million deaths or 14.6% of human deaths. The most common types of cancer in males are lung cancer, prostate cancer, colorectal cancer and stomach cancer. In females, the most common types are breast cancer, colorectal cancer, lung cancer and cervical cancer. If skin cancer other than melanoma were included in total new cancers each year it would account for around 40% of cases. In children, acute lymphoblastic leukaemia and brain tumors are most common except in Africa where non-Hodgkin lymphoma occurs more often. In 2012, about 165,000 children under 15 years of age were diagnosed with cancer. The risk of cancer increases significantly with age and many cancers occur more commonly in developed countries. Rates are increasing as more people live to an old age and as lifestyle changes occur in the developing world. The financial costs of cancer were estimated at $1.16 trillion US dollars per year as of 2010.
Definitions.
Cancers are a large family of diseases that involve abnormal cell growth with the potential to invade or spread to other parts of the body. They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often form a mass or lump, but may be distributed diffusely., A lymph node or lymph gland, is an ovoid or kidney-shaped organ of the lymphatic system, and of the adaptive immune system, that is widely present throughout the body. They are linked by the lymphatic vessels as a part of the circulatory system. Lymph nodes are major sites of B and T lymphocytes, and other white blood cells. Lymph nodes are important for the proper functioning of the immune system, acting as filters for foreign particles and cancer cells. Lymph nodes do not have a detoxification function, which is primarily dealt with by the liver and kidneys., Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is therapy using ionizing radiation, generally as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology., Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. Melanomas typically occur in the skin but may rarely occur in the mouth, intestines, or eye. In women they most commonly occur on the legs, while in men they are most common on the back. Sometimes they develop from a mole with concerning changes including an increase in size, irregular edges, change in color, itchiness, or skin breakdown.
The primary cause of melanoma is ultraviolet light (UV) exposure in those with low levels of skin pigment. The UV light may be from either the sun or from other sources, such as tanning devices. About 25% develop from moles. Those with many moles, a history of affected family members, and who have poor immune function are at greater risk. A number of rare genetic defects such as xeroderma pigmentosum also increase risk. Diagnosis is by biopsy of any concerning skin lesion.
Using sunscreen and avoiding UV light may prevent melanoma. Treatment is typically removal by surgery. In those with slightly larger cancers, nearby lymph nodes may be tested for spread. Most people are cured if spread has not occurred. For those in whom melanoma has spread, immunotherapy, biologic therapy, radiation therapy, or chemotherapy may improve survival. With treatment the five-year survival rates in the United States is 98% among those with localized disease and 17% among those in whom spread has occurred. The likelihood that it will come back or spread depends how thick the melanoma is, how fast the cells are dividing, and whether or not the overlying skin has broken down.
Melanoma is the most dangerous type of skin cancer. Globally, in 2012, it occurred in 232,000 people and resulted in 55,000 deaths. Australia and New Zealand have the highest rates of melanoma in the world. There are also high rates in Northern Europe and North America, while it is less common in Asia, Africa, and Latin America. Melanoma is more common in men than women. Melanoma has become more common since the 1960s in areas that are mostly Caucasian., Subject: ivan vyshnevskyi, Relation: cause_of_death, Options: (A) bleeding (B) breast cancer (C) cancer (D) carcinoma (E) disease (F) hepatitis (G) lung cancer (H) melanoma (I) old age (J) skin cancer (K) tumor

Answer: skin cancer


Question: Context: Constance of York , Countess of Gloucester , ( c. 1374 -- 28 November 1416 ) was the only daughter of Edmund of Langley , 1st Duke of York and his wife Isabella of Castile , daughter of King Peter of Castile and his favourite mistress , María de Padilla ., Lionel of Antwerp, 1st Duke of Clarence, "jure uxoris" 4th Earl of Ulster and 5th Baron of Connaught, KG (29 November 13387 October 1368) was the third son, but the second son to survive infancy, of Edward III of England and Philippa of Hainault. He was named for his birthplace, at Antwerp in the Duchy of Brabant. Prince Lionel was born of a Flemish mother and was a grandson of William I, Count of Hainaut. He grew to be nearly seven feet in height and had an athletic build., The House of York was a cadet branch of the English royal House of Plantagenet. Three of its members became Kings of England in the late 15th century. The House of York was descended in the male line from Edmund of Langley, 1st Duke of York, the fourth surviving son of Edward III, but also represented Edward's senior line, being cognatic descendants of Lionel, Duke of Clarence, Edward III's second surviving son. It is based on these descents that they claimed the English crown. Compared with the House of Lancaster, it had a senior claim to the throne of England according to cognatic primogeniture but junior claim according to the agnatic primogeniture. The reign of this dynasty ended with the death of Richard III of England in 1485. It became extinct in the male line with the death of Edward Plantagenet, 17th Earl of Warwick in 1499., The House of Lancaster was the name of two cadet branches of the royal House of Plantagenet. The first house was created when Henry III of England created the Earldom of Lancasterfrom which the house was namedfor his second son Edmund Crouchback in 1267. Edmund had already been created Earl of Leicester in 1265 and was granted the lands and privileges of Simon de Montfort, 6th Earl of Leicester, after de Montfort's death and attainder at the end of the Second Barons' War. When Edmund's son Thomas, 2nd Earl of Lancaster, inherited his father-in-law's estates and title of Earl of Lincoln he became at a stroke the most powerful nobleman in England, with lands throughout the kingdom and the ability to raise vast private armies to wield power at national and local levels. This brought himand Henry, his younger brotherinto conflict with their cousin Edward II of England, leading to Thomas's execution. Henry inherited Thomas's titles and he and his son, who was also called Henry, gave loyal service to Edward's sonEdward III of England., John of Gaunt, 1st Duke of Lancaster, (6 March 1340  3 February 1399) was a member of the House of Plantagenet, the third of five surviving sons of King Edward III of England and Philippa of Hainault. He was called "John of Gaunt" because he was born in Ghent, then rendered in English as "Gaunt". When he became unpopular later in life, scurrilous rumours and lampoons circulated that he was actually the son of a Ghent butcher, perhaps because Edward III was not present at the birth. This story always drove him to fury., Edmund of Langley, 1st Duke of York, (5 June 1341  1 August 1402) was the fourth surviving son of King Edward III of England and Philippa of Hainault. Like many medieval English princes, Edmund gained his nickname from his birthplace: Kings Langley Palace in Hertfordshire. He was the founder of the House of York, but it was through the marriage of his younger son, Richard of Conisburgh, 3rd Earl of Cambridge, to Anne de Mortimer, great-granddaughter of Edmund's elder brother Lionel of Antwerp, 1st Duke of Clarence, that the House of York made its claim to the English throne in the Wars of the Roses. The other party in the Wars of the Roses, the incumbent House of Lancaster, was formed from descendants of Edmund's elder brother John of Gaunt, 1st Duke of Lancaster, Edward III's third son., Subject: constance of york, Relation: noble_family, Options: (A) grandson (B) house of lancaster (C) house of plantagenet (D) house of york

Answer:
house of york