Basic and simple mathematical model of coupled transcription, translation and degradation

26 Apr 2012Alexander N. GorbanAnnick Harel-BellanNadya MorozovaAndrei Zinovyev

Synthesis of proteins is one of the most fundamental biological processes, which consumes a significant amount of cellular resources. Despite many efforts to produce detailed mechanistic mathematical models of translation, no basic and simple kinetic model of mRNA lifecycle (transcription, translation and degradation) exists... (read more)

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