A Modality-Adaptive Method for Segmenting Brain Tumors and Organs-at-Risk in Radiation Therapy Planning

18 Jul 2018Mikael AgnPer Munck af RosenschöldOula PuontiMichael J. LundemannLaura ManciniAnastasia PapadakiSteffi ThustJohn AshburnerIan LawKoen Van Leemput

In this paper we present a method for simultaneously segmenting brain tumors and an extensive set of organs-at-risk for radiation therapy planning of glioblastomas. The method combines a contrast-adaptive generative model for whole-brain segmentation with a new spatial regularization model of tumor shape using convolutional restricted Boltzmann machines... (read more)

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